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Relationship between Evaluation for the Self and others and Anhedonia in Patients with Schizophrenia

Kim MK, Kim ES, Lee JS, Kim EJ, Kim J, Kim JJ

OBJECTIVES: The dysfunctional neural networks underlying self-evaluation in schizophrenia are overlapped with the neural structures involved in emotion regulation. The purpose of this study was to investigate the influence of...
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Brain Regions Associated With Anhedonia in Healthy Adults: a PET Correlation Study

Jung YC, Seok JH, Chun J, Park HJ, Lee JD, Kim JJ

  • KMID: 2307642
  • Korean J Nucl Med.
  • 2005 Dec;39(6):438-444.
PURPOSE: Anhedonia has been proposed to be the result of a basic neurophysiologic dysfunction and a vulnerability marker that precede and contribute to the liability of developing schizophrenia. We hypothesized...
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A case of atrophy of bilateral frontal lobe which showed negative symptoms of schizophrenia

Rho TY, Kim JS

  • KMID: 2320423
  • Yeungnam Univ J Med.
  • 1993 Dec;10(2):544-549.
The authors have experienced a case of organic mental disorder with bilateral frontal lobe atrophy in. a 36-year-old man. He showed negative symptoms of schizophrenia such as anhedonia, social withdrawal, flat...
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Aberrant Tendency of Noncurrent Emotional Experiences in Individuals at Ultra-High Risk for Psychosis

Seo E, Bang M, Lee E, An SK

OBJECTIVE: This study aimed to investigate whether aberrant tendency of noncurrent emotion was present in individuals at ultra-high risk (UHR) for psychosis and to explore its associations with various clinical...
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Anhedonia and Ambivalence in Schizophrenic Patients with Fronto-Cerebellar Metabolic Abnormalities: A Fluoro-D-Glucose Positron Emission Tomography Study

Park KM, Kim JJ, Seok JH, Chun JW, Park HJ, Lee JD

  • KMID: 2315820
  • Psychiatry Investig.
  • 2009 Jun;6(2):72-77.
OBJECTIVE: Prefrontal and cerebellar abnormalities have been associated with higher cognitive deficits in schizophrenia. The current study aimed to show whether or not schizophrenic patients with fronto-cerebellar functional abnormalities show...
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Abnormalities in Inflammatory Cytokines Confer Susceptible to Chronic Neuropathic Pain-related Anhedonia in a Rat Model of Spared Nerve Injury

Fang X, Zhan G, Zhang J, Xu H, Zhu B, Hu Y, Yang C, Luo A

OBJECTIVE: Patients with chronic neuropathic pain (CNP) have a higher incidence to develop depression. However, its pathogenesis has not yet been fully elucidated. Here we aimed to investigate the role...
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Influence of Anhedonia and Self-Esteem on Daily-Life Decision-Making in Patients with Schizophrenia

Kim SJ, Kim MK, Hong YJ, Lee SK, Kim JJ

OBJECTIVES: Decision-making in patients with schizophrenia has been known to be inefficient in both cognitive and affective aspects. The purpose of this study was to investigate the influence of anhedonia...
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Comparison of the Characteristics of Anhedonia between Patients with Schizophrenia and Depressive Disorder

Choi SH, Park IH, Ku J, Choi KM, Park M, Kim JJ

  • KMID: 2341823
  • J Korean Neuropsychiatr Assoc.
  • 2010 Nov;49(6):570-577.
OBJECTIVES: Anhedonia, defined as an inability to experience pleasure, has been considered to be a core feature of schizophrenia and depression. The purpose of the present study was to compare...
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Deficits in Abstract Thinking Assessed by Theme Identification in Patients with Schizophrenia

Oh J, Chun JW, Kim JJ

OBJECTIVES: Patients with schizophrenia often have a concrete thinking or an impairment in abstract thinking, but there has been a limitation in quantitatively measuring this cognitive function. The aim of...
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The Reliability and Validity of the Korean Version of Apathy Evaluation Scale and its Application in Patients with Schizophrenia

Lee YM, Park IH, Koo MS, Ko SY, Kang HM, Song JE

OBJECTIVES: Apathy Evaluation Scale (AES) is one of the most frequently used scales to evaluate apathy. The purpose of this study was to evaluate the reliability and validity of the...
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Deficit of Executive Control of Positive Emotional Information and Its Association with Social Anhedonia in Schizophrenia

Park JS, Chun JW, Park IH, Kim ES, Kim JJ

OBJECTIVES: Schizophrenia has been considered to be characterized by an abnormality in attention, especially in the executive control. Emotion is an important component of the executive control. The aim of...
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The Characteristics of Associative Learning of Reward Approach and Loss Aversion in Schizophrenia

Park S, Kim SH, Park IH, Kim JH, Kim JJ, Koo MS, Song J

OBJECTIVES: Schizophrenia patients have deficits of prediction and learning related to dopaminergic dysfunction. It is hypothesized that there would be different characteristics in associative learning of reward approach and loss...
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The Role of Cytokines in Depresstion and Their Therapeutic Implication

KIm YK

  • KMID: 2286935
  • Korean J Psychopharmacol.
  • 2000 Dec;11(4):304-312.
The aims of this article is to review the current knowledge on the role of cytokines in depression by discussing the brain action of cytokines, their role in the stress...
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Major Depressive Disorder Preceding the Onset of Progressive Supranuclear Palsy

Kim WH, Lee YS, Jung SH, Choi HJ, Lee MJ, Kang MH, Kim CE, Lee JS, Bae JN

  • KMID: 2315826
  • Psychiatry Investig.
  • 2009 Jun;6(2):112-114.
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by vertical supranuclear palsy and parkinsonian symptoms. The neuropsychiatric symptoms of PSP include anhedonia, depressed mood and cognitive impairment. Patients with...
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Vitamin D Deficiency/Insufficiency among Inpatients with Depressive Symptoms

Woo YS, Kim S, Jeong JH, Jung YE, Kim MD, Bahk WM

OBJECTIVE: Although the association between low vitamin D levels and depressive symptoms has been widely reported, studies investigating the relationship between hypovitaminosis D and depressive symptomatology are scarce. METHODS: We retrospectively...
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Dandy Walker Variant and Bipolar I Disorder with Graphomania

Can SS, Karakas Ugurlu G, Cakmak S

  • KMID: 2316357
  • Psychiatry Investig.
  • 2014 Jul;11(3):336-339.
Cerebellum is known to play an important role in coordination and motor functions. In some resent studies it is also considered to be involved in modulation of mood, cognition and...
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Anhedonia and Dysphoria Are Differentially Associated with the Risk of Dementia in the Cognitively Normal Elderly Individuals: A Prospective Cohort Study

Lee JR, Suh SW, Han JW, Byun S, Kwon SJ, Lee KH, Kwak KP, Kim BJ, Kim SG, Kim JL, Kim TH, Ryu SH, Moon SW, Park JH, Lee DW, Youn JC, Lee DY, Lee SB, Lee JJ, Jhoo JH, Kim KW

OBJECTIVE: We investigated the impact of depressed mood (dysphoria) and loss of interest or pleasure (anhedonia)on the risk of dementia in cognitively-normal elderly individuals. METHODS: This study included 2,685 cognitively-normal elderly...
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Protective Effects of Curcumin and Sertraline on the Behavioral Changes in Chronic Variable Stress-Induced Rats

Noorafshan A, Abdollahifar MA, Karbalay-Doust S, Asadi-Golshan R, Rashidian-Rashidabadi A

Behavioral characteristics of the animal models and humans are impaired in chronic stress. The present study aimed to evaluate and compare the protective effects of sertraline and curcumin on stress-induced...
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Treatment of Burning Mouth Syndrome: A report of 2 cases

Kim BS, Sung CH, Yoon KJ, Lee DW, Yang SY, Park CM, Moon DE

  • KMID: 2199694
  • J Korean Pain Soc.
  • 2003 Dec;16(2):217-220.
Burning mouth syndrome is a clinical entity characterized by a painful, burning sensation in the oral area, with no visual mucosal abnormalities on clinical examination. Affected patients often present with...
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Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis

Ham S, Kim TK, Chung S, Im HI

Addictive drug use or prescribed medicine abuse can cause psychosis. Some representative symptoms frequently elicited by patients with psychosis are hallucination, anhedonia, and disrupted executive functions. These psychoses are categorized...
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