J Korean Radiol Soc.  1985 Aug;21(4):604-609. 10.3348/jkrs.1985.21.4.604.

Value of bone scintigraphy for pre-, postoperative assessment and follow-up study of breast cancer

• Lee HG
• Park JM
• Chung SK
• Kim CY
• Bahk YW

• KMID: 2462437
• DOI: http://doi.org/10.3348/jkrs.1985.21.4.604

Abstract

Early detection of neoplastic disese and metastatic spred is very important. Carcinoma of the breast is knownto readily metastasize to the bone. The use of Tc-99m-phophate as bone imaging agent has been shown to demonstrate early evidence of bone metastasis well before radiographic evidence is visualized and as thus become a very usefultechnique for establishing and monitoring the bony metastatic element of breast cancer. In this study, serial boneimaging studies were performed to monitor the management of 84 breast cancer patients before and after mastectomyand biopsy. We attempted to analyse bone scans of breast cancer and to correlated the scan findings with theclinical stage, status of lymphnodes, distanat metastasis, bone pain, and laboratory datas. The following useful patterns were emerged: 1. Postive bone scan rate was definitely higher in clinical stage III and IV (42, 57%) thatin stage I and II(4, 18%) in initital studies. However, no correlation between positive bone scan rate andclinical stage was found in follow up studies. 2. Positive bone scan rate was high in both groups with locallyadvanced tumor(T3 & T4) and distant metastasis. 3. No correlation between postive bone scan and status oflymphnode involvement was noted. 4. Positive bone scan rate was also very high in patients with bone pain andabnomral laboratory data.

MeSH Terms

Biopsy
Breast Neoplasms*
Breast*
Follow-Up Studies*
Humans
Neoplasm Metastasis
Radionuclide Imaging*