Ann Dermatol.  2019 Dec;31(6):681-683. 10.5021/ad.2019.31.6.681.

A Case of Desmoplastic Melanoma in a Patient with Parkinson's Disease

Affiliations
  • 1Department of Dermatology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea. jyroh1@gilhospital.com

Abstract

No abstract available.


MeSH Terms

Humans
Melanoma*
Parkinson Disease*

Figure

  • Fig. 1 (A) An erythematous crusted papule with violaceous sclerotic surrounding plaque on the nose. (B) High magnification showing characteristic bundles of malignant, (C) spindle-shaped cells in dermis admixed with collagen bundles. (D) Desmoplastic melanoma with neurotropic features showing malignant spindle-shaped cells tended to invade around nerves (H&E, original magnification: B, ×200; C, ×400; D, ×400).

  • Fig. 2 (A) Histopathologic examination shows positive results for S-100 protein, (B) CD 68, (C) cyclin D, (D) Trichrome, for infiltrating spindle-shaped cells (A~D: original magnification ×200).


Reference

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5. Disse M, Reich H, Lee PK, Schram SS. A review of the association between parkinson disease and malignant melanoma. Dermatol Surg. 2016; 42:141–146.
Article
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