Psychiatry Investig.
2019 Sep;16(9):704-712. 10.30773/pi.2019.06.20.2.
Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder
- Affiliations
-
- 1Department of Psychiatry, Eulji University Hospital, Daejeon, Republic of Korea.
- 2Department of Psychiatry and Electroconvulsive Therapy Center, Dongguk University International Hospital, Goyang, Republic of Korea. ciwkjs@gmail.com
- 3Institute of Clinical Psychopharmacology, Dongguk University College of Medicine, Goyang, Republic of Korea.
- 4Department of Anesthesiology and Pain Medicine, Dongguk University International Hospital, Goyang, Republic of Korea.
- KMID: 2459691
- DOI: http://doi.org/10.30773/pi.2019.06.20.2
Abstract
OBJECTIVE
The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BP-BL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors.
METHODS
Among 67 patients who received ECT and diagnosed with schizophrenia/schizoaffective disorder based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, we included 56 patients who received 1-millisecond BP-BL ECT after anesthesia with sodium thiopental between March 2012 and June 2018. Demographic and clinical information was gathered from electronic medical records, and a multiple regression analysis was conducted to identify predictors of the IST.
RESULTS
The mean age of the patients was 36.9±12.0 years and 30 (53.6%) patients were male. The mean and median IST were 105.9±54.5 and 96 millicoulombs (mC), respectively. The IST was predicted by age, gender, and dose (mg/kg) of sodium thiopental. Other physical and clinical variables were not associated with the IST.
CONCLUSION
The present study demonstrated that the IST of 1-ms BP-BL ECT following sodium thiopental anesthesia in Korean patients was comparable to those reported in previous literature. The IST was associated with age, gender, and dose of sodium thiopental.
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