Korean J Pathol.  2009 Aug;43(4):382-385.

Cytologic Diagnosis of Malignant Pleural Effusion in Multiple Myeloma: Two Case Reports

Affiliations
  • 1Department of Pathology, Chonnam National University Medical School, Gwangju, Korea. cchoi@chonnam.ac.kr
  • 2Brain Korea 21 Project, Center for Biomedical Human Resources at Chonnam National University, Gwangju, Korea.

Abstract

Malignant pleural effusion in multiple myeloma (MM) is extremely rare and is associated with poor prognosis. We experienced two cases of MM IgA type with malignant pleural effusion. The diagnoses were based on characteristic cytology and CD138 immunocytochemistry. The patients received several cycles of combination chemotherapy, since symptoms were more aggressive with an uncontrolled pleural effusion. We review the clinical features of these cases and literature concerning myelomatous pleural effusion.

Keyword

Cytology; Malignant pleural effusion; Multiple Myeloma

MeSH Terms

Drug Therapy, Combination
Humans
Immunoglobulin A
Immunohistochemistry
Multiple Myeloma
Pleural Effusion
Pleural Effusion, Malignant
Prognosis
Immunoglobulin A
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