Korean J Ophthalmol.  2019 Oct;33(5):467-474. 10.3341/kjo.2019.0060.

Evaluation of the Protective Effect of an Ophthalmic Viscosurgical Device on the Ocular Surface in Dry Eye Patients during Cataract Surgery

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. jyhyon@snu.ac.kr
  • 2Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 3Seoul Balgeunsesang Eye Clinic, Seoul, Korea.
  • 4Department of Ophthalmology, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Korea.

Abstract

PURPOSE
To evaluate the protective effect of applying an ophthalmic viscosurgical device (OVD) to the ocular surface during cataract surgery and its ability to prevent dry eye syndrome.
METHODS
Twenty-four patients aged 50 to 75 years who underwent cataract surgery at Seoul National University Bundang Hospital and agreed to participate in the study were included and divided into two groups: a study group who underwent cataract surgery after application of an OVD to the ocular surface, and a control group who underwent cataract surgery without application of an OVD. DisCoVisc was used as the OVD in the study group, while other factors including surgical techniques and administration of anesthetic agents were performed in both groups in the same manner. Indicators of dry eye syndrome including ocular staining score, tear break-up time, and tear osmolality were analyzed. Ocular surface disease index and a visual analog scale were analyzed for dry eye symptoms, and the amount of balanced salt solution used during surface irrigation and operation time were also analyzed.
RESULTS
Significant improvement in the tear break-up time, corneal ocular staining score, and ocular surface disease index score in the study group compared with the control group one week after operation (by the Mann-Whitney test). Use of OVD was associated with longer operating time.
CONCLUSIONS
OVD applied to the ocular surface during cataract surgery had a protective effect on the ocular surface one week after surgery.

Keyword

Cataract extraction; Dry eye syndromes; Ophthalmic viscosurgical device

MeSH Terms

Anesthetics
Cataract Extraction
Cataract*
Dry Eye Syndromes
Humans
Osmolar Concentration
Seoul
Tears
Visual Analog Scale
Anesthetics

Figure

  • Fig. 1 Differences between preoperative and postoperative dry eye evaluation values at 1 week and 1 month after cataract. (A) Tear break-up time (BUT), (B) tear osmolality (Osm), (C) corneal ocular staining score (OSS), (D) conjunctival ocular staining score, (E) ocular surface disease index (OSDI), and (F) visual analog scale (VAS).


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