Tuberc Respir Dis.  2019 Oct;82(4):269-276. 10.4046/trd.2018.0090.

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 1. Introduction

• Park SW
• Baek AR
• Lee HL
• Jeong SW
• Yang SH
• Kim YH
• Chung MP
• on behalf of the Korean Interstitial Lung Diseases Study Group

• KMID: 2459050
• DOI: http://doi.org/10.4046/trd.2018.0090

Abstract

Idiopathic interstitial pneumonia (IIP) is a histologically identifiable pulmonary disease without a known cause that usually infiltrates the lung interstitium. IIP is largely classified into idiopathic pulmonary fibrosis, idiopathic non-specific interstitial pneumonia, respiratory bronchiolitis-interstitial lung disease (ILD), cryptogenic organizing pneumonia, desquamative interstitial pneumonia, and acute interstitial pneumonia. Each of these diseases has a different prognosis and requires specific treatment, and a multidisciplinary approach that combines chest high-resolution computed tomography (HRCT), histological findings, and clinical findings is necessary for their diagnosis. Diagnosis of IIP is made based on clinical presentation, chest HRCT findings, results of pulmonary function tests, and histological findings. For histological diagnosis, video-assisted thoracoscopic biopsy and transbronchial lung biopsy are used. In order to identify ILD associated with connective tissue disease, autoimmune antibody tests may also be necessary. Many biomarkers associated with disease prognosis have been recently discovered, and future research on their clinical significance is necessary. The diagnosis of ILD is difficult because patterns of ILD are both complicated and variable. Therefore, as with other diseases, accurate history taking and meticulous physical examination are crucial.

Keyword

Lung Diseases, Interstitial; Idiopathic Interstitial Pneumonias; Classification; Diagnosis

MeSH Terms

Biomarkers
Biopsy
Classification
Connective Tissue Diseases
Cryptogenic Organizing Pneumonia
Diagnosis*
Idiopathic Interstitial Pneumonias
Idiopathic Pulmonary Fibrosis
Lung
Lung Diseases
Lung Diseases, Interstitial*
Physical Examination
Prognosis
Respiratory Function Tests
Thorax
Biomarkers

Figure

• 

  Figure 1 Classification of interstitial lung disease (ILD). ILD can be primarily classified with and without known causes. Known etiologies of ILD were occupational or environmental exposures, drugs, radiation, connective tissue diseases and so on.

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