Ann Dermatol.  2018 Aug;30(4):508-509. 10.5021/ad.2018.30.4.508.

Plexiform Schwannoma with Localized Hypertrichosis

Affiliations
  • 1Department of Dermatology, Pusan National University School of Medicine, Busan, Korea. hcko@pusan.ac.kr
  • 2Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, Korea.
  • 3Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.

Abstract

No abstract available.


MeSH Terms

Hypertrichosis*
Neurilemmoma*

Figure

  • Fig. 1 Solitary brownish nodule with localized hypertrichosis on the left leg.

  • Fig. 2 (A) Multiple variable-sized, encapsulated, and interconnected nodules (H&E, ×40). (B) Nodules composed of spindle cells with focally palisading nuclei (H&E, ×100). (C) Tumor cells in the nodules strongly stained for S-100 protein (S-100 protein staining, ×100). (D) The capsules of the nodules stained for epithelial membrane antigen (EMA, ×200). (E) Neurofilament staining of the cells in the nodules was negative (neurofilament staining, ×100).


Reference

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3. Ko JY, Kim JE, Kim YH, Ro YS. Cutaneous plexiform schwannomas in a patient with neurofibromatosis type 2. Ann Dermatol. 2009; 21:402–405.
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4. Wagamon K, Mirmirani P. Localized hypertrichosis in a pediatric patient--what is the mechanism for excess hair growth? Pediatr Dermatol. 2007; 24:250–252.
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5. Botchkarev VA, Kishimoto J. Molecular control of epithelial-mesenchymal interactions during hair follicle cycling. J Investig Dermatol Symp Proc. 2003; 8:46–55.
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