J Korean Soc Radiol.  2019 Jul;80(4):810-814. 10.3348/jksr.2019.80.4.810.

Primary Effusion Lymphoma in a Non-Human Immunodeficiency Virus Patient: A Case Report

• Kim BJ
• Lee MS

• KMID: 2457463
• DOI: http://doi.org/10.3348/jksr.2019.80.4.810

Abstract

Primary effusion lymphoma is a large cell non-Hodgkin lymphoma exclusively presenting with effusions in body cavities in absence of solid tumor masses. It is typically associated with human herpesvirus 8 infection in immunocompromised patients with human immunodeficiency virus (HIV) infection. We report herein a case of primary effusion lymphoma in a HIV-negative patient.

MeSH Terms

Herpesvirus 8, Human
HIV
Humans
Immunocompromised Host
Lymphoma, Non-Hodgkin
Lymphoma, Primary Effusion*
Pericardial Effusion
Pleural Effusion

Figure

• 

  Fig. 1 Primary effusion lymphoma in an 81-year-old male. A. Non-enhanced chest CT showing a large amount of pericardial effusion and pleural effusion in the posterior dependent portion of both sides of the chest. B. Follow-up enhanced chest CT performed 2 weeks after pericardiocentesis shows increased amounts of pleural effusion, especially on the left side, and recurrence of pericardial effusion. C. Immunohistochemistry for human HHV-8-encoded LANA demonstrated positive, stippled nuclear staining in atypical pleomorphic lymphoid cells with abundant cytoplasm and prominent nucleoli (HHV-8 LANA immunostain, × 200). HHV-8 = human herpesvirus-8, LANA = latency-associated nuclear antigen

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