J Gynecol Oncol.  2019 Sep;30(5):e78. 10.3802/jgo.2019.30.e78.

The efficacy of modified Swede Colposcopic Index in prediction of high-grade lesion and cancer of cervix

• Rodpenpear N
• Pataradool K

• KMID: 2457156
• DOI: http://doi.org/10.3802/jgo.2019.30.e78

Abstract

OBJECTIVE
To evaluate the efficacy of modified Swede Colposcopic Index (MSCI) to predict high-grade lesion and cancer of cervix (CIN2+, cervical intraepithelial neoplasia grade 2 or worse) in women with abnormal cervical cytology who underwent a colposcopy.
METHODS
We conducted a retrospective study and MSCI using 5 features of cervical lesions evidenced from colposcopy: acetouptake, margin and surface, vessels, lesion size, and location of lesion. Each feature was scored from cervicograhpic findings which transformation zone was completely seen. Odds ratio of each feature was obtained by logistic regression analysis. Receiver operating characteristic curve was used to assess the efficacy of summation score to predict CIN2+. An appropriate cut-off point score was assigned.
RESULTS
Two hundred and twenty women were included in the study. The assigned score for each factor in level 1 to 3 was 1, 2 and 3 points with a total score of 15 points. The most appropriate cut-off points score for MSCI to predict CIN2+ was 11 points. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy using MSCI were 82.2%, 96.2%, 96.0%, 85.0%, and 90.0% respectively.
CONCLUSION
MSCI showed a high efficacy for predicting CIN2+ in satisfactory colposcopy.

Keyword

High-Grade Squamous Intraepithelial Lesions; Cervical Cancer; Colposcopy

MeSH Terms

Cervical Intraepithelial Neoplasia
Colposcopy
Female
Humans
Logistic Models
Odds Ratio
Retrospective Studies
ROC Curve
Sensitivity and Specificity
Squamous Intraepithelial Lesions of the Cervix
Uterine Cervical Neoplasms*