Ann Clin Neurophysiol.  2018 Jul;20(2):57-65. 10.14253/acn.2018.20.2.57.

Application of near-infrared spectroscopy in clinical neurology

• Kim YH
• Kim BJ
• Bae JS

• KMID: 2454706
• DOI: http://doi.org/10.14253/acn.2018.20.2.57

Abstract

Near-infrared spectroscopy (NIRS) monitoring has been used mainly to detect reduced perfusion of the brain during orthostatic stress in order to assess orthostatic intolerance (OI). Many studies have investigated the use of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurological diseases (e.g., stroke, epilepsy, and migraine) is continuing. NIRS may play an important role in monitoring the regional distribution of the hemodynamic flow in real time and thereby reveal the underlying pathophysiology and facilitate the management of not only patients with OI symptoms but also those with various neurological diseases.

Keyword

Orthostatic intolerance; Near-infrared spectroscopy; Clinical neurology

MeSH Terms

Brain
Epilepsy
Hemodynamics
Humans
Neurology*
Orthostatic Intolerance
Perfusion
Spectroscopy, Near-Infrared*
Stroke

Figure

• 

  Fig. 1 Absorption spectra of oxygenated hemoglobin (HbO), deoxygenated hemoglobin (HbR), and water.

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  Fig. 2 Near-infrared light paths in the human brain from the light source to the photodetector.

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  Fig. 3 Arrangement of the photo and laser diodes.

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  Fig. 4 A clinical application of NIRS. NIRS, near-infrared spectroscopy.

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