J Vet Sci.
2019 Mar;20(2):e9. 10.4142/jvs.2019.20.e9.
Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016
- Affiliations
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- 1Veterinary Drugs and Biologics Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea. yihee@korea.kr
- 2Veterinary Pharmaceutical Management Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea.
- 3Avian Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea.
- 4Laboratory of Histopathology, Department of Clinical Laboratory Science, Semyung University, Jecheon 27136, Korea. ghwoo@naver.com
- KMID: 2454012
- DOI: http://doi.org/10.4142/jvs.2019.20.e9
Abstract
- Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity in wild birds. AChE activity was measured in the brains of 87dead wild birds (26 species). The level of AChE activity ranged from 6.40 to 15.9 µmol/min/g of brain tissue in normal wild birds. However, the brain tissue AChE activity level in wild birds exposed to organophosphate (OP) pesticide was 48.0%-96.3% of that in the normal birds. These results may serve as reference values to facilitate routine diagnosis and monitoring of OP-poisoned wild birds.
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