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Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016

Bang JH, Ku HO, Kang HG, Kim H, Kim S, Park SW, Kim YS, Jang I, Bae YC, Woo GH, Yi H

Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity...
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Sudden death caused by trichlorfon poisoning in Korean native cattle

Kim JH, Lee K, Jung JY, Yi H, Sohn JH, So B, Choi EJ

Two 12-month-old cattle with anthelmintics containing trichlorfon the day before death presented to the Animal and Plant Quarantine Agency for diagnosis. In necropsy, they revealed enlargement of the spleens, redness...
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Different Clinical Courses for Poisoning with WHO Hazard Class Ia Organophosphates EPN, Phosphamidon, and Terbufos in Humans

Mun JG, Moon JM, Lee MJ, Chun BJ

PURPOSE: Extremely hazardous pesticides are classified as World Health Organization (WHO) hazard class Ia. However, data describing the clinical course of WHO class Ia OP (organophosphate) poisonings in humans are...
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Relative Risk and Clinical Severity Assessment in Patients with Non-Oral Route Organophosphate Poisoning Compared with Oral Route Poisoning

Jung WJ, Yu MH, Lee Y, Kim H, Cha YS, Park KH

PURPOSE: Organophosphates, commonly used in agricultural pesticides, pose high risks and incidences of poisoning. In the present study, we investigated the relative risk and clinical severity, including laboratory results, of...
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Methidathion Poisoning

Kim KH, Kim SH, Her C

Although methidathion is an organophosphate insecticide, it is different from the other organophosphates in terms of toxicity. Because of its relatively high fat solubility, the apparent volume of methidathion distribution...
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Acute Kidney Injury after Intravenous Injection of an Organophosphate Compound

Lee JY, Sung WY, Lee IY, Seo SW, Lee WS

Poisoning may result from self-injection. Previous reports have described acute cholinergic crisis, intermediate syndrome, and delayed toxicity resulting from parenteral organophosphate administration. These complications have been managed with antidotal and...
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Initial Blood Glucose Can Predict the Outcome of OP Poisoning

Lee SD, Moon JM, Chun BJ

  • KMID: 2133229
  • J Korean Soc Clin Toxicol.
  • 2015 Dec;13(2):55-61.
PURPOSE: Many studies have examined the mechanisms of impaired glucose homeostasis after organophosphate (OP) exposure, however no study has evaluated the clinical utility of blood glucose measurements in patients with...
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Hepatitis B surface antigen levels at 6 months after treatment can predict the efficacy of lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B

Kim JH, Moon HW, Ko SY, Choe WH, Kwon SY

BACKGROUND/AIMS: Quantitation of hepatitis B surface antigen (HBsAg) is an increasingly popular method to determine the treatment response in chronic hepatitis B (CHB) patients. The clinical value of HBsAg level...
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Left Facial Swelling Caused by Organophosphate (Dichlorvos) Poisoning: A Case Report and Review of the Literature

Park DH

  • KMID: 2333843
  • J Korean Soc Emerg Med.
  • 2014 Jun;25(3):318-322.
In organophosphate intoxication, the neurotransmitter acetylcholine accumulates in synapses, causing excessive stimulation of nicotinic and muscarinic receptors, producing various signs and symptoms. Organophosphates are highly toxic compounds that are readily...
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Trends of Lipase and General Features in Organophosphates Induced Acute Pancreatitis

Cho NH, Kim H, Jung WJ, Kim YW, Kim TH, Kim OH, Cha KC, Lee KH, Hwang SO, Cha YS

  • KMID: 2333837
  • J Korean Soc Emerg Med.
  • 2014 Jun;25(3):277-283.
PURPOSE: There have been few case reports and studies on acute pancreatitis associated with organophosphate (OP) poisoning. We investigated prevalence, general characteristics, trends of lipase levels, and findings of computed...
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Clinical Significance of National Patients Sample Analysis: Factors Affecting Mortality and Length of Stay of Organophosphate and Carbamate Poisoned Patients

Kim KH, Kwon IH, Lee JY, Yeo WH, Park HY, Park KH, Cho J, Kim H, Kim GB, Park DH, Yoon YS, Kim YW

OBJECTIVES: This study considered whether there could be a change of mortality and length of stay as a result of inter-hospital transfer, clinical department, and size of hospital for patients...
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Basal Level of Cholinesterase in a Population of Residents Over 60 Years Old in Jeju

Park KH, Kim WJ, Kang YJ, Park JH, Park JO, Kim H

  • KMID: 2192128
  • J Korean Soc Emerg Med.
  • 2012 Jun;23(3):383-388.
PURPOSE: Measurement of pseudocholinesterase (PChE) is a simple test for evaluation of the severity of intoxication with organophosphate and carbamate insecticides, because they inhibit PChE; however, as demonstrated in several...
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Appropriateness of Adenosine Deaminase-Guided Management for Patients with Pericardial Effusion

Kim NY, Min JH, Ahn JH, Cho SY, Lee EJ, Hwang SJ, Park Y, Kwak CH, Hwang JY, Park JR

  • KMID: 2264293
  • Korean J Med.
  • 2012 Apr;82(4):441-448.
BACKGROUND/AIMS: The prognostic impact of empirical anti-tuberculous management according to adenosine deaminase (ADA) levels in patients exhibiting pericardial effusion (PE) has not been established. We evaluated the appropriateness of ADA-guided...
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A Case of Amitraz Poisoning Initially Misdiagnosed as Acute Organophosphate Insecticide Poisoning

Cho Y, Kim JW

  • KMID: 2317669
  • Soonchunhyang Med Sci.
  • 2012 Dec;18(2):151-154.
Amitraz is acaricidal and insecticidal pesticide used worldwide to control ticks and mites in plants and animals. Amitraz poisoning is characterized by clinical toxidrome such as central nervous system, respiratory...
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Occupational Neurotoxic Diseases in Taiwan

Liu CH, Huang CY, Huang CC

  • KMID: 2317070
  • Saf Health Work.
  • 2012 Dec;3(4):257-267.
Occupational neurotoxic diseases have become increasingly common in Taiwan due to industrialization. Over the past 40 years, Taiwan has transformed from an agricultural society to an industrial society. The most...
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Optimized Internal Control and Gene Expression Analysis in Epstein-Barr Virus-Transformed Lymphoblastoid Cell Lines

Nam HY, Kim HR, Shim SM, Lee JE, Kim JW, Park HK, Han BG, Jeon JP

  • KMID: 1806238
  • Genomics Inform.
  • 2011 Sep;9(3):127-133.
The Epstein-Barr virus-transformed lymphoblastoid cell line (LCL) is one of the major genomic resources for human genetics and immunological studies. Use of LCLs is currently extended to pharmacogenetic studies to...
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Clinical Outcome for High-dose Pralidoxime in Treating Organophosphate Intoxication

Lee KM, Choi YH, Cheon YJ, Lee DH

  • KMID: 2101636
  • J Korean Soc Clin Toxicol.
  • 2011 Dec;9(2):56-60.
PURPOSE: The optimal dose of oximes for use in the treatment of organophosphorus pesticide poisoning has not been conclusively established. In this retrospective study, we assessed the effectiveness of the...
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A Case of Amyotrophic Lateral Sclerosis in a Worker Treating Pesticide Wastes

Choy S, Kim JW

  • KMID: 2028557
  • Korean J Occup Environ Med.
  • 2011 Dec;23(4):480-487.
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease involving the motor neuron of the cerebrum, brain stem, and spinal cord. It has been suggested that various occupational or environmental...
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A Case of Bentazone Poisoning Mimicking Organophosphate Intoxication

Jung HM, Kim JH, Han SB, Paik JH, Kim JY, Kim JS

  • KMID: 2203738
  • J Korean Soc Clin Toxicol.
  • 2010 Dec;8(2):122-124.
Basagran(R) is a herbicide that is widely used in the field and it acts by interfering with photosynthesis in plants. It consists of bentazone, 2-methyl-4-chloro phenoxyacetic acid (MCPA) and surfactants....
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Scoring Methods for Prognosis of Patients with Acute Severe Organophosphate Intoxication

Ha TW, Han YJ, Yoo SJ

  • KMID: 2192625
  • J Korean Soc Emerg Med.
  • 2009 Dec;20(6):673-679.
PURPOSE: Although, there have been many reports about factors involved in the severity and prognosis of organophosphate toxicity, there are few reports on integrated application of scoring methods using those...
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