Int J Thyroidol.  2018 Nov;11(2):167-171. 10.11106/ijt.2018.11.2.167.

A Case of Intrathyroid Thyroglossal Duct Cyst

Affiliations
  • 1Department of Otorhinolaryngology, School of Medicine, Gyeongsang National University, Jinju, Korea.capetown@gnu.ac.kr
  • 2Institute of Health Sciences, School of Medicine, Gyeongsang National University, Jinju, Korea.
  • 3Department of Pathology, School of Medicine, Gyeongsang National University, Jinju, Korea.
  • 4Department of Pediatrics, School of Medicine, Gyeongsang National University, Jinju, Korea.

Abstract

An intrathyroid thyroglossal duct cyst (TGDC) presented as an anterior neck mass in a 62-year-old male without history of prior thyroid disease or infection. This cyst was clinically indistinguishable from a thyroid nodule. In addition to that, fine needle aspiration cytology revealed normal-looking squamous cells. Diagnosis, work-up, management approach, and treatment of intrathyroid TGDC are discussed as well as distinguishing features between intrathyrod TGDC with tract and without tract. This is the very rare case of intrathyroid TGDC in Korean population and the possibility of intrathyroid TGDC should remain in the differential diagnosis of thyroid nodule.

Keyword

Thyglossal duct cyst; Thyroid gland; Neck

MeSH Terms

Biopsy, Fine-Needle
Diagnosis
Diagnosis, Differential
Epithelial Cells
Humans
Male
Middle Aged
Neck
Thyroglossal Cyst*
Thyroid Diseases
Thyroid Gland
Thyroid Nodule

Figure

  • Fig. 1. Thyroid ultrasound images and ultrasound guided fine-needle aspiration (FNA) image of left thyroid gland. 2.2×1.2×3.0 cm sized pre-dominantly cystic lesion (A). This FNA image is only liquid-based acellular specimen (B). After 1 year, 0.9×0.3×1.8 cm sized cystic lesion with calcified debri (C). Only visible many benign- looking squamous cells (D). After 2 years, 0.9×0.3×1.6 cm sized predominantly cystic lesion with calcified debris (E). This FNA image is visible few follicular cells (F).

  • Fig. 2. Computed tomography and light microscopic image of pathologic specimen. The hypodense lesion (white arrows) is located in the left thyroid gland. (A) Axial view,(B) Coronal view. Histopathological examination. Hema-toxylin-Eosion staining (H&E staining); the thyroid nodule showed the squamous epithelium lining and pseudo-stratified ciliated columnar cells with thyroid follicles in the sur-rounding colloid. (C) (x 100), (D) (x 400).


Reference

1). Ellis PD, van Nostrand AW. The applied anatomy of thyroglossal tract remnants. Laryngoscope. 1977; 87(5 Pt 1):765–70.
Article
2). Persaud R, Short M, Kothari P, Robinson A. Thyroglossal duct cyst masquerading as a haematoma. J Laryngol Otol. 2004; 118(3):240–1.
Article
3). Athow AC, Fagg NL, Drake DP. Management of thyroglossal cysts in children. Br J Surg. 1989; 76(8):811–4.
Article
4). Choi HJ, Jung JH, Yoo J, Kang SJ, Lee KY, Chun CS, et al. Intrathyroid thyroglossal duct cyst: A case report. Korean J Pathol. 2007; 41(2):132–4.
5). McHenry CR, Danish R, Murphy T, Marty JJ. Atypical thyroglossal duct cyst: a rare cause for a solitary cold thyroid nodule in childhood. Am Surg. 1993; 59(4):223–8.
6). Sonnino RE, Spigland N, Laberge JM, Desjardins J, Guttman FM. Unusual patterns of congenital neck masses in children. J Pediatr Surg. 1989; 24(10):966–9.
Article
7). Johnston R, Wei JL, Maddalozzo J. Intrathyroid thyroglossal duct cyst as a differential diagnosis of thyroid nodule. Int J Pediatr Otorhinolaryngol. 2003; 67(9):1027–30.
Article
8). Huang LD, Gao SQ, Dai RJ, Chen DD, He B, Shi HQ, et al. Intrathyroid thyroglossal duct cyst: a case report and review of literature. Int J Clin Exp Pathol. 2015; 8(6):7229–33.
9). Hatada T, Ichii S, Sagayama K, Ishii H, Sugihara A, Terada N, et al. Intrathyroid thyroglossal duct cyst simulating a thyroid nodule. Tumori. 2000; 86(3):250–2.
Article
10). Perez-Martinez A, Bento-Bravo L, Martinez-Bermejo MA, Conde-Cortes J, de Miguel-Medina C. An intrathyroid thyroglossal duct cyst. Eur J Pediatr Surg. 2005; 15(6):428–30.
Article
11). North JH Jr, Foley AM, Hamill RL. Intrathyroid cysts of thyroglossal duct origin. Am Surg. 1998; 64(9):886–8.
12). Alvarez Garcia N, Burgues Prades P, Gonzalez Martinez-Pardo N, Simon Portero S, Fernandez Atuan R. The intrathyroid thyroglossal cyst in the differential diagnosis of the solitary thyroid nodule: A presentation of 2 cases. An Pediatr (Barc). 2015; 82(5):360–1.
13). Pelausa ME, Forte V. Sistrunk revisited: a 10-year review of revision thyroglossal duct surgery at Toronto's Hospital for Sick Children. J Otolaryngol. 1989; 18(7):325–33.
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