Korean J Pancreas Biliary Tract.  2016 Jan;21(1):11-18. 10.15279/kpba.2016.21.1.11.

Assessment of Severity and Fluid Administration in Acute Pancreatitis

• Lee YS
• Cho KB

• KMID: 2448506
• DOI: http://doi.org/10.15279/kpba.2016.21.1.11

Abstract

Acute pancreatitis is one of the potentially life-threatening diseases with a wide spectrum of severity. The estimated mortality rate for all patients with acute pancreatitis is approximately 5%. Severe pancreatitis often takes a clinical course with two overlapping phases, an early and a late phase, with two peaks of mortality. According to the revised Atlanta classification system, acute pancreatitis can be divided into mild, moderately severe, or severe. It is important to identify patients with potentially severe acute pancreatitis who require aggressive early treatment. It is believed that intravenous fluid resuscitation is an important variable for improved outcomes in acute pancreatitis. Most guidelines encourage targeting fluid resuscitation toward correcting hypotension, correcting hemoconcentration, and maintaining adequate urine output. In this review article, I would like to discuss the assessment of severity and fluid administration in acute pancreatitis.

Keyword

Acute pancreatitis; Severity; Fluid therapy

MeSH Terms

Classification
Fluid Therapy
Humans
Hypotension
Mortality
Pancreatitis*
Resuscitation