Korean J Pancreas Biliary Tract.
2015 Oct;20(4):222-227. 10.15279/kpba.2015.20.4.222.
Acute Necrotizing Pancreatitis during L-asparaginase Treatment in a Patient with Acute Lymphoblastic Leukemia
- Affiliations
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- 1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. hjkimmd@korea.ac.kr
- KMID: 2448501
- DOI: http://doi.org/10.15279/kpba.2015.20.4.222
Abstract
- L-asparaginase is an important component of antileukemic therapy in patients with acute lymphoblastic leukemia. The degree of L-asparaginase toxicity is variable. Several cases of L-asparaginase related pancreatitis have been reported in the literature. However, necrotizing pancreatitis in adult has not been reported yet. Herein, we present a case of necrotizing pancreatitis caused by L-asparaginase that was complicated by pancreatic duct leakage and pseudocyst formation, but successfully treated with percutaneous drainage and octreotide treatment.
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