Korean J Parasitol.
2019 Apr;57(2):153-159. 10.3347/kjp.2019.57.2.153.
Prevalence and Molecular Characterization of Echinococcus granulosus Sensu Stricto in Northern Xinjiang, China
- Affiliations
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- 1College of Animal Science and Technology, Shihezi University, Road Beisi, Shihezi 832003, Xinjiang, PR China. 215273439@qq.com
- 2Veterinary Research Institute, Xinjiang Academy of Animal Sciences, 726 Street Dongrong, North Gaoxin District, Urumqi 830000, Xinjiang, PR China.
- 3State Key Laboratory for Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asian, First Affiliated Hospital of Xinjiang Medical University, Road Liyushan, Urumqi 830054, Xinjiang, PR China.
- 4Xinjiang Key Laboratory of Medical Animal Model Research, Clinical Medical Research Institute of First Affiliated Hospital of Xinjiang Medical University, Road Liyushan, Urumqi 830011, Xinjiang, PR China.
- 5The Friendship Hospital of Yili Kazak Autonomous Prefecture, 92 Road Stalin, Yining 835000, Xinjiang, PR China.
- 6Basic Medical College of Xinjiang Medical University, Road Liyushan, Urumqi 830011, Xinjiang, PR China.
- KMID: 2448146
- DOI: http://doi.org/10.3347/kjp.2019.57.2.153
Abstract
- Echinococcus granulosus is an important zoonotic parasite globally causing cystic echinococcosis (CE) in humans and animals. In this study, prevalence of CE and variation of cox1 gene sequence were analyzed with isolates E. granulosus collected from different areas in northern Xinjiang, China. The survey showed that 3.5% of sheep and 4.1% of cattle were infected with CE. Fragment of cox1 was amplified from all the positive sheep and cattle samples by PCR. In addition, 26 positive samples across the 4 areas were included. The isolates were all E. granulosus sensu stricto (s.s.) containing 15 haplotypes (Hap1-15), and clustered into 2 genotypes, G1 (90.1%, 91/101) and G3 (9.9%, 10/101). Hap1 was the most common haplotype (48.5%, 49/101). Hap9 were found in humans samples, indicating that sheep and cattle reservoir human CE. It is indicate that E. granulosus may impact on control of CE in livestock and humans in the region.
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