Korean J Med.  2018 Oct;93(5):473-476. 10.3904/kjm.2018.93.5.473.

Praziquantel Treatment of Eosinophilic Gastritis Suspected to Be Due to Cerebral Sparganosis

Affiliations
  • 1Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea. pinetrees@daum.net
  • 2Department of Anatomic Pathology, Kangwon National University School of Medicine, Chuncheon, Korea.

Abstract

Eosinophilic gastritis is characterized by eosinophilic infiltration of the gastrointestinal tract, which is associated with abdominal pain, diarrhea, nausea, and vomiting. The possible etiologies of secondary eosinophilic gastritis, including drug reactions, parasitic infestation, and malignancy, must be evaluated. Herein we report the case of a 65-year-old North Korean defector who presented with nausea and vomiting for 1 year. Secondary (reactive) eosinophilic gastritis caused by cerebral sparganosis was suspected after a workup that included brain magnetic resonance imaging, cerebrospinal fluid tapping, and gastric mucosal biopsy. The patient showed dramatic clinical improvement with high-dose praziquantel treatment. Even though secondary (reactive) eosinophilic gastritis caused by parasites is very rare, this case shows the importance of considering parasitic infection in eosinophilic gastritis.

Keyword

Eosinophilic gastritis; Parasite; Sparganosis; Praziquantel

MeSH Terms

Abdominal Pain
Aged
Biopsy
Brain
Cerebrospinal Fluid
Diarrhea
Eosinophils*
Gastritis*
Gastrointestinal Tract
Humans
Magnetic Resonance Imaging
Nausea
Parasites
Praziquantel*
Sparganosis*
Vomiting
Praziquantel
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