Mood Emot.  2018 Mar;16(1):1-12. 10.0000/me.2018.16.1.1.

Korean Medication Algorithm for Bipolar Disorder 2018: Overview

• Kim W
• Bahk WM
• Yoon BH
• Jon DI
• Seo JS
• Lee JG
• Woo YS
• Jeong JH
• Kim MD
• Sohn I
• Shim SH
• Song HR
• Min KJ

• KMID: 2446840
• DOI: http://doi.org/10.0000/me.2018.16.1.1

Abstract

OBJECTIVES
The Korean Medication Algorithm for Bipolar Disorder (KMAP-BP), which was first published in 2002 and updated in 2006, 2010 and 2014, is revised again through the expert's consensus of opinion.
METHODS
Out of eighty-four member of the review committee, sixty-one members completed the survey. We analyzed the answers, and thus discussed the data and held a clinician hearing on the results. Therefore, we report the results of KMAP-BP 2018.
RESULTS
The preferred first-step strategies for acute euphoric mania are the combination of mood stabilizer (MS) and atypical antipsychotics (AAP), MS monotherapy and AAP monotherapy. For psychotic mania, combination of MS and AAP, and AAP monotherapy are preferred. The first-step strategies for acute bipolar, mild to moderate, depression are MS monotherapy, lamotrigine (LTG) monotherapy, AAP monotherapy, MS+AAP combination, AAP+LTG combination and MS+LTG combination. For non-psychotic severe depression, the MS+AAP combination, AAP+LTG combination and MS+LTG combination are preferred. For psychotic severe depression, the MS+AAP, AAP+antidepressant (AD) and AAP+LTG are preferred.
CONCLUSION
We surveyed the expert consensus for the treatment of bipolar disorders and developed KMAP-BP 2018. We hope that this KMAP-BP 2018 is going to be helpful for clinicians to treat the patients with bipolar disorder.

Keyword

Bipolar disorder; KMAP-BP 2018, Pharmacotherapy; Algorithm

MeSH Terms

Advisory Committees
Antipsychotic Agents
Bipolar Disorder*
Consensus
Depression
Hearing
Hope
Humans
Antipsychotic Agents