Mood Emot.  2018 Nov;16(3):129-133. 10.0000/me.2018.16.3.129.

Korean Medication Algorithm for Bipolar Disorder 2018 : Medical Comorbidity

Affiliations
  • 1Department of Psychiatry, Myongji Hospital, Goyang, Korea.
  • 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. wmbahk@catholic.ac.kr
  • 3Department of Psychiatry, Naju National Hospital, Naju, Korea. yoonbh@chollian.net
  • 4Department of Psychiatry, Sacred Heart Hospital, Hallym University, Anyang, Korea.
  • 5Department of Psychiatry, School of Medicine, Konkuk University, Chungju, Korea.
  • 6Department of Psychiatry, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
  • 7Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University and Paik Institute for Clinical Research, Busan, Korea.
  • 8Department of Health Science and Technology, Graduate School of Inje University, Busan, Korea.
  • 9Department of Psychiatry, Jeju National University Hospital, Jeju, Korea.
  • 10Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, Korea.
  • 11Department of Psychiatry, Soonchunhyang University Cheonan Hospital, Soonchunhyang University, Cheonan, Korea.
  • 12Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract


OBJECTIVES
The fourth revision of Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) was performed in 2018, to provide newer guidelines for clinicians. In this section, we examined expert opinions to facilitate clinical decisions relative to treating bipolar disorder with medical comorbidity.
METHODS
The survey was completed by the review committee, consisting of 61 experienced psychiatrists. This part of the survey constitutes treatment strategies, under major medical comorbidities. The executive committee analyzed results, and discussed the final production of algorithm.
RESULTS
Aripiprazole was the first-line medication for bipolar patients with metabolic syndrome, cardiovascular, hepatic, renal, and cerebrovascular comorbidities. Ziprasidone also was recommended as the first-line medication in case of metabolic syndrome. Lithium also was regarded as the first-line medication, in case of hepatic problems. Valproate also was considered as the first-line medication, in case of cerebrovascular problems.
CONCLUSION
This study provided the most recent consensus among experts, for treatment of bipolar disorder with physical problems.

Keyword

Bipolar disorder; Medical comorbidity; Pharmacotherapy; Algorithm

MeSH Terms

Advisory Committees
Aripiprazole
Bipolar Disorder*
Comorbidity*
Consensus
Drug Therapy
Expert Testimony
Humans
Lithium
Psychiatry
Valproic Acid
Aripiprazole
Lithium
Valproic Acid
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