Pediatr Infect Vaccine.  2019 Apr;26(1):42-50. 10.14776/piv.2019.26.e5.

Clinical Features of Staphylococcal Scalded Skin Syndrome Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Changwon City, Korea, during 2006 and 2015

  • 1Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, the Republic of Korea.
  • 2Department of Pediatrics, Changwon Fatima Hospital, Changwon, the Republic of Korea.
  • 3Department of Microbiology, Kyungpook National University School of Medicine, Daegu, the Republic of Korea.


We investigated the clinical features and epidemiology of staphylococcal scalded skin syndrome (SSSS) from year 2006 to 2015 in Changwon city, Korea.
We reviewed medical records of 69 patients diagnosed with SSSS from year 2006 to 2015. Antibiotic susceptibility testing was performed by agar dilution method. Methicillin-resistant Staphylococcus aureus (MRSA) was phenotypically identified by oxacillin susceptibility testing and genotypically confirmed by the existence of the mecA gene.
The median age of patients was 2.0 years (range 0.2-6 years). Three (4.3%), 53 (76.8%), and 13 (18.9%) patients showed the generalized type, the intermediate type, and the abortive type, respectively. Patients occurred throughout the year, but most patients occurred between July and October. MRSA was isolated from 54 of the 60 patients regardless of the clinical types. All patients recovered without any complications.
There was a constant occurrence of SSSS patients caused by MRSA in Changwon area during 2006 and 2015. It is needed to constantly monitor the occurrence of patients with SSSS.


Stahylococcal scalded skin syndrome; Staphylococcus aureus

MeSH Terms

Medical Records
Methicillin Resistance*
Methicillin-Resistant Staphylococcus aureus*
Staphylococcal Scalded Skin Syndrome*
Staphylococcus aureus


  • Fig. 1 Age distribution of SSSS patients. Abbreviation: SSSS, staphylococcal scalded skin syndrome.

  • Fig. 2 (A) Yearly distribution of SSSS patients. (B) Monthly distribution of SSSS patients. Abbreviation: SSSS, staphylococcal scalded skin syndrome.


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