Kosin Med J.  2018 Dec;33(3):422-430. 10.7180/kmj.2018.33.3.422.

Bacteremia caused by Leuconostoc species : 6-case series

  • 1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. dongsik72@hanmail.net
  • 2Department of Molecular Cell Biology, Sungkyunkwan University College of Medicine, Suwon, Korea.


Leuconostoc species are Gram-positive coccobacilli and are used in dairy products and are intrinsically resistant to vancomycin. Leuconostoc infections are rare in humans, usually occurring in immune-compromised patients. We describe 6 patients with Leuconostoc bacteremia at Dong-A university hospital between 1990 and 2015. One isolate (L. lactis) was identified to species level using 16S rRNA gene sequencing analysis. All patients had underlying diseases and 5 patients underwent procedures that interrupted the normal integumentary defense. Four patients died within 30 days after being identified as carrying Leuconostoc species.


Bacteremia; Leuconostoc; Vancomycin resistance

MeSH Terms

Dairy Products
Genes, rRNA
Vancomycin Resistance


  • Fig. 1. The phylogenetic relationships of isolate DAU-03 with other related Leuconostoc strains based on 16S rRNA gene sequences


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