Kosin Med J.  2018 Dec;33(3):422-430. 10.7180/kmj.2018.33.3.422.

Bacteremia caused by Leuconostoc species : 6-case series

• Oh KJ
• Jung DS
• Ko KS
• Lee HJ
• Park JY
• Lee H

• KMID: 2442555
• DOI: http://doi.org/10.7180/kmj.2018.33.3.422

Abstract

Leuconostoc species are Gram-positive coccobacilli and are used in dairy products and are intrinsically resistant to vancomycin. Leuconostoc infections are rare in humans, usually occurring in immune-compromised patients. We describe 6 patients with Leuconostoc bacteremia at Dong-A university hospital between 1990 and 2015. One isolate (L. lactis) was identified to species level using 16S rRNA gene sequencing analysis. All patients had underlying diseases and 5 patients underwent procedures that interrupted the normal integumentary defense. Four patients died within 30 days after being identified as carrying Leuconostoc species.

Keyword

Bacteremia; Leuconostoc; Vancomycin resistance

MeSH Terms

Bacteremia*
Dairy Products
Genes, rRNA
Humans
Leuconostoc*
Vancomycin
Vancomycin Resistance
Vancomycin

Figure

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  Fig. 1. The phylogenetic relationships of isolate DAU-03 with other related Leuconostoc strains based on 16S rRNA gene sequences

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