Korean J Intern Med.  2019 Mar;34(2):418-425. 10.3904/kjim.2017.203.

Epidemiology of urticaria including physical urticaria and angioedema in Korea

Affiliations
  • 1Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea. legent@hanmail.net
  • 2Department of Allergy and Clinical Immunology, Kangwon National University School of Medicine, Chuncheon, Korea.

Abstract

BACKGROUND/AIMS
Despite the high burden and frequency of urticaria, its epidemiology is not well known. We investigated the epidemiology of various type of urticaria in Korea and changes in its annual prevalence over 5 years.
METHODS
We used data from the 2010 to 2014 Health Insurance Review and Assessment database, which covers the claims of 97.0% of the South Korean population. Patients aged > 10 years old were included in this study. The presence of urticaria was identified on physician-certified diagnoses using the International Classification of Diseases 10th Revision (ICD-10) codes that include various type of urticaria (L500-L509) and angioedema (T783). Epidemiology of all type of urticaria, physical urticaria and angioedema were investigated.
RESULTS
The prevalence of all-type urticaria over the 5 years was 4.5% with a peak in individuals, especially females, aged 30 to 59 years. The age-specific prevalence of all-type urticaria increased with age from the 10- to 19-year age group to the 70- to 79-year age group. The prevalence of dermographism, cholinergic urticaria, and angioedema were 0.12%, 0.025%, and 0.027%, respectively. Cholinergic urticaria was most prevalent in those aged 10 to 29 years with male predominance. The annual prevalence of all-type urticaria, dermographism, and angioedema increased over the 5 years.
CONCLUSIONS
The prevalence of urticaria has increased annually in Korea. Cholinergic urticaria showed unique distribution in its age and gender, and angioedema showed remarkable increases in annual prevalence, although the prevalence estimation is still exploratory and diagnosis of urticaria based on ICD-10 codes need to be validated.

Keyword

Urticaria; Angioedema; Epidemiology; Prevalence; Republic of Korea

MeSH Terms

Angioedema*
Diagnosis
Epidemiology*
Female
Humans
Insurance, Health
International Classification of Diseases
Korea*
Male
Prevalence
Republic of Korea
Urticaria*
Full Text Links
  • KJIM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr