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Omalizumab on Chronic Spontaneous Urticaria and Chronic Inducible Urticaria: A Real-World Study of Efficacy and Predictors of Treatment Outcome

Jeong SH, Lim DJ, Chang SE, Kim KH, Kim KJ, Park EJ

Background Omalizumab is a very important drug for the treatment of chronic urticaria. Although omalizumab’s therapeutic efficacy has been demonstrated, data on real-world experiences in Korea, especially regarding chronic inducible urticaria...
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Analysis of Predictive Factors of Response to Omalizumab Treatment in Chronic Spontaneous Urticaria Patients

Lee HY, Koo DW, Lee JS

  • KMID: 2522537
  • Korean J Dermatol.
  • 2021 Nov;59(9):685-692.
Background: The European Academy of Allergy and Clinical Immunology guideline for the management of urticaria published in 2018 recommends adding omalizumab as a third-line therapy. However, data on the potential...
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Acute urticarial rash after COVID-19 vaccination containing Polysorbate 80

Burlando M, Herzum A, Cozzani E, Parodi A

We present the case of a 48-year-old Caucasian woman, who developed an acute urticarial rash after the second dose of coronavirus disease 2019 (COVID-19) vaccination with Oxford-AstraZeneca. Though the most...
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Aquagenic Urticaria Treated with Omalizumab

Ha YJ, Jung SY, Lee SG, Park CS

Aquagenic urticaria is a rare form of physical urticaria in which a 1-2 mm wheal is produced by contact with water. Treatment options include antihistamines, ultraviolet monotherapy, topical barrier creams,...
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Treatment of Solar Urticaria with Ultraviolet A1 Hardening Phototherapy

Cheon HI, Kim SM, Hong JY, Cho YA, Son HS, Lee YW, Choe YB, Ahn KJ

  • KMID: 2517088
  • Korean J Dermatol.
  • 2021 Jun;59(5):409-410.
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An Analysis of the Clinical and Photobiological Characteristics of Solar Urticaria: A 15-year Retrospective Study

Hong JY, Lee YW, Choe YB, Ahn KJ

  • KMID: 2514431
  • Korean J Dermatol.
  • 2021 Mar;59(3):206-211.
Background: Solar urticaria (SU) is a rare type of photodermatosis characterized by the appearance of itchy wheals and erythema within minutes after exposure to sunlight or artificial light. Only a...
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Omalizumab for Cyclosporine-resistant Chronic Spontaneous Urticaria: A Retrospective Study of a Single Center

Kim HJ, Kim Wi, Shin K, Son JH, Lee WK, Kim HS, Kim B, Kim MB, Ko HC

  • KMID: 2514427
  • Korean J Dermatol.
  • 2021 Mar;59(3):175-180.
Background: Cyclosporine is a recommended third-line treatment for chronic spontaneous urticaria (CSU) that is resistant to H1-antihistamines according to the EAACI/GA 2 LEN/EDF/WAO guidelines for management of urticaria. However, some...
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Neutrophilic Urticarial Dermatosis Accompanied with Bullous Lesions

Yoo DS, Kim JH, Kim SC

  • KMID: 2509676
  • Korean J Dermatol.
  • 2020 Dec;58(10):701-703.
Neutrophilic urticarial dermatosis (NUD) clinically resembles urticaria but histopathologically represents a neutrophilic dermatoses. Affected patients develop erythematous macules, papules or slightly raised plaques lasting 24 to 48 hours. Histopathologic examination...
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Anxiety, depression, and stress in Korean patients with chronic urticaria

Choi GS, Nam YH, Park CS, Kim MY, Jo EJ, Park HK, Kim HK

Background/Aims: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to...
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The Relation of Autologous Serum Skin Test andAutologous Plasma Skin Test Result with VariousClinical and Laboratory Findings in Patients withChronic Spontaneous Urticaria

Park GH, Choi JH, Kim S, Bae Y

Background: Despite the autologous serum skin test (ASST)and autologous plasma skin test (APST) is widely used test accessingwhether a patient with chronic spontaneous urticaria(CSU) has autoreactivity or not, the clinician...
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Anaphylaxis induced by sugammadex and sugammadex-rocuronium complex -a case report-

Choi SC, Han S, Kwak J, Lee JY

Background: In sugammadex-induced anaphylaxis, sugammadex and/or sugammadex-rocuronium complex have possible allergenic epitope. Case: We report a case of sugammadex-induced anaphylaxis during general anesthesia in a 60-year-old male undergoing...
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Health-Related Utility of EQ-5D in Korean Adults With Chronic Urticaria: Mapping From Urticaria Outcome Measures

Lee MS, Yoon J, Kim J, Shin YS, Park HS, Lee HY, Ye YM

Purpose: A need for useful measures reflective of the socio-economic burden of chronic urticaria (CU) has arisen. To obtain utility estimates for CU, we investigated EuroQol-5-Dimension (EQ-5D) indices according to...
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The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 1. Definition, Methodology and First-line Management

Song WJ, Choi M, Lee DH, Kwon JW, Kim GW, Kim MH, Kim MA, Kim MH, Kim BK, Kim S, Kim JS, Kim JE, Kim JY, Kim JH, Kim HJ, Kim HO, Kim HB, Roh JY, Park KH, Park KY, Park HK, Park H, Bae JM, Byun JY, Song DJ, Ahn YM, Lee SE, Lee YB, Lee JS, Lee JH, Lim KH, Ye YM, Chang YS, Jeon YH, Jeon J, Jue MS, Choi SH, Choi JH, Hur GY, Park YM, Lim DH, Youn SW

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated...
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Natural History of Chronic Urticaria in Korea

Chung BY, Um JY, Kang SY, Kim HO, Park CW

BACKGROUND: Data on the natural history and prognostic variables of chronic urticaria (CU) are rare and information about spontaneous remission of CU is limited. OBJECTIVE: This study evaluated the natural history...
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Update on the Management of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity

Yeung WY, Park HS

The clinical phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity are heterogeneous with various presentations including time of symptom onset, organ involvements, and underlying pathophysiology. Having a correct diagnosis can be...
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Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review

Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P

PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic...
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Urticaria: Classification and Diagnosis

Ye YM

Urticaria is a common cutaneous disease characterized by recurrent and transient wheals and pruritus, sometimes accompanied angioedema. The classification of urticaria is based on the duration of the disease and...
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Anaphylaxis to Chlorpheniramine Maleate and Literature Review

Choi YW, Jung MJ, Kim HO, Chung BY, Park CW

Chlorpheniramine maleate is commonly used antihistamine. Since antihistamines are the main therapeutic agents for symptomatic treatment of urticaria, anaphylaxis to antihistamines may lead to errors in diagnosis and treatment. We...
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The First Case Series of Cryopyrin-Associated Periodic Syndrome in Korea

Han JH, Je YJ, Yoon HJ, Ahn JG, Lee JS, Park JW, Park HJ

Cryopyrin-associated periodic syndrome (CAPS) is a hereditary autoinflammatory syndrome caused by mutations in NLRP3 (encoding cryopyrin), which presents with fever, fatigue and arthralgia. Thus far, however there have been no...
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Cold Urticaria: Clinical Features and Natural Course in a Tropical Country

Kulthanan , Tuchinda P, Chularojanamontri L, Kiratiwongwan R

PURPOSE: To review the clinical features and natural courses of cold urticaria (ColdU) in a tropical country. METHODS: A retrospective chart review was performed of patients who visited Siriraj Urticaria Clinic,...
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