Korean J Pediatr Infect Dis.  2006 Nov;13(2):130-136. 10.14776/kjpid.2006.13.2.130.

The Causative Organisms of Neonatal and Pediatric Bacterial Meningitis in Korea(2000~2005)

• Jeon YS
• Lee SY
• Mok HR
• Lee JH
• Kim JH
• Hur JK
• Kang JH

• KMID: 2439980
• DOI: http://doi.org/10.14776/kjpid.2006.13.2.130

Abstract

PURPOSE
The purpose of this study is to confirm the epidemiologic change of the causative organisms of neonatal and pediatric bacterial meningitis in Korea. And we tried to evaluate the risk factors correlated with prognosis which was available on the day of admission.
METHODS
Retrospectively, we reviewed the medical records of 57 patients admitted for bacterial meningitis at six hospitals affiliated with Catholic Medical Center for 6 years(Jan. 2000~Dec. 2005).
RESULTS
22 cases(38.6%) of them were neonates under 28 days and 35 cases were infants and children ; 16 cases(28.1%), under 1 year ; 6 cases(10.5%), under 5 years ; 13 cases (22.8%), under 15 years. In neonates, 16 cases(72.7%) were caused by group B streptococcus (GBS). In infants and children, S. pneumoniae(25.7%), H. influenzae type b(Hib)(22.8%) and N. meningitidis(22.8%) were common cause of bacterial meningitis in order. In the informations available on the day of admission, weight deficit for age under 3 percentile, increased CRP level and decreased glucose level of CSF were related to poor prognosis(P < 0.05).
CONCLUSION
GBS became a leading cause of neonatal bacterial meningitis. Though, pneumoccocal, Hib and meningococcal meningitis were confirmed as major causes of bacterial meningitis. The routine immunization of pneumococcal and Hib vaccines will be considered, and it is necessary to introduce meningococcal vaccines to our country in the future.

Keyword

Bacterial meningitis; Causative organisms; Neonate; Infants and Children

MeSH Terms

Child
Glucose
Haemophilus influenzae type b
Humans
Immunization
Infant
Infant, Newborn
Influenza, Human
Korea
Medical Records
Meningitis, Bacterial*
Meningitis, Meningococcal
Meningococcal Vaccines
Prognosis
Retrospective Studies
Risk Factors
Streptococcus
Vaccines
Glucose
Meningococcal Vaccines
Vaccines