Clin Pain.  2018 Dec;17(2):74-80. 10.0000/cp.2018.17.2.74.

Epidural Neuroplasty with Single Bolus Injection versus Continuous Infusion of Steroid in Patients with Spinal Stenosis

• Lee BC
• Eun JD
• Rho HW
• Kim ES
• Kwon JY
• Kim SJ

• KMID: 2439563
• DOI: http://doi.org/10.0000/cp.2018.17.2.74

Abstract

OBJECTIVE
To compare the efficacy of epidural adhesiolysis with a single bolus steroid injection (EAS) and continuous steroid infusion (EAC). METHOD: Thirty-one patients were allocated to the EAS group (10 patients) and EAC group (21 patients). EAS received single bolus of 10 mg of dexamethasone. EAC received a total of 96 mL dexamethasone solution (20.0 mg of dexamethasone) for 48 hrs. Oswestry Disability Index (ODI) was evaluated before, one month after the procedure. Three months after the procedure, the Patient's Global Impression of Change (PGIC) was evaluated.
RESULTS
Pre-treatment ODI was 38.3 ± 3.1 in EAS and 46.40 ± 4.0 in EAC. One month later, ODI was decreased to 35.60 ± 3.33, 43.08 ± 6.96 in each group (p=0.174). Three months later, 2 patients in the EAS (20.0%) and 8 patients in EAC (38.1%) showed "˜much improvement' in PGIC, 5 patients in EAS (50.0%) and 6 patients in EAC (38.1%) showed "˜slight improvement', 3 patients in EAS (30.0%) and 7 patients in EAC (33.3%) showed "˜no improvement' (χ2=1.588, p=0.510).
CONCLUSION
Epidural adhesiolysis with continuous infusion did not show any superiority than single bolus injection.

Keyword

Spinal Stenosis; Epidural Adhesiolysis; Corticosteroid; Continuous Infusion

MeSH Terms

Dexamethasone
Humans
Methods
Spinal Stenosis*
Dexamethasone