J Korean Ophthalmol Soc.  2019 Feb;60(2):103-108. 10.3341/jkos.2019.60.2.103.

Molluscum Contagiosum of the Eyelid Margin: a Case Series and Literature Review

• Jang Y
• Kim N
• Khwarg SI
• Choung HK

• KMID: 2438068
• DOI: http://doi.org/10.3341/jkos.2019.60.2.103

Abstract

PURPOSE
We report 9 cases of molluscum contagiosum of the eyelid margin and a literature review.
METHODS
A retrospective, observational case series of 9 patients who were diagnosed with molluscum contagiosum of the eyelid margin.
RESULTS
Subjects included 8 female patients and 1 male patient with an average age of 6.1 years. The patients were all healthy without any underlying disease, and their blood analyses and chest X-rays excluded any infectious disease or immune-related problem. Each patient had 1-6 skin lesions. Hematoxylin and eosin staining revealed lobular hyperplasia of the squamous epithelium, which invaded into the underlying dermis. Staining also revealed inclusion bodies in the cytoplasm of keratinocytes above the basal layer. All patients were maintained without complications or recurrence after surgical treatment.
CONCLUSIONS
Molluscum contagiosum on the eyelid margin differs from those on other body parts. Subjects had fewer lesions and lesion shapes were atypical. Early surgical treatment may be necessary because molluscum contagiosum can lead to ocular complications such as conjunctivitis.

Keyword

Eyelid diseases; Histologic diagnosis; Molluscum contagiosum

MeSH Terms

Communicable Diseases
Conjunctivitis
Cytoplasm
Dermis
Eosine Yellowish-(YS)
Epithelium
Eyelid Diseases
Eyelids*
Female
Hematoxylin
Human Body
Humans
Hyperplasia
Inclusion Bodies
Keratinocytes
Male
Molluscum Contagiosum*
Recurrence
Retrospective Studies
Skin
Thorax
Eosine Yellowish-(YS)
Hematoxylin

Figure

• 

  Figure 1 Clinical photographs and histopathologic findings of patients. (A, B) Case 1. (C, D) Case 2. (E, F) Case 3. (G, H) Case 4. All the patients had small, flesh-colored mass on the eyelid margin (A, C, E, G), and pathologic examination revealed multiple lobular hyperplasia of squamous epithelium invading into the dermis with large, homogenous inclusion bodies in the keratinocytes displacing the cell nucleus peripherally (arrows in H) (hematoxylin and eosin stain, ×40 [B, D, F], ×100 [H]).

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