Korean J Med.  2019 Feb;94(1):124-128. 10.3904/kjm.2019.94.1.124.

Malignant Melanoma of the Pancreas and Liver Mimicking a Neuroendocrine Tumor

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mhkim@amc.seoul.kr
  • 2Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Among metastatic pancreatic tumors, malignant melanomas are rare. Here, we report a very rare case of a malignant melanoma that involved only the pancreas and liver, and was difficult to differentiate from a neuroendocrine tumor of the pancreas with a liver metastasis. A 65-year-old- male with no history of a malignant melanoma exhibited hypervascular hepatic and pancreatic tumors on computed tomography and contrast-enhanced endoscopic ultrasonography. He lacked lesions of the skin, eye, and gastrointestinal tract on physical examination, upper endoscopy, and a whole-body positron emission tomography-computed tomography scan; these sites are common primary sites of malignant melanoma. Finally, endoscopic ultrasound-guided pancreatic core biopsy and percutaneous ultrasonography-guided liver biopsy confirmed malignant melanoma of the pancreas and liver.

Keyword

Pancreatic neoplasms; Melanoma; Neuroendocrine tumors

MeSH Terms

Biopsy
Electrons
Endoscopy
Endosonography
Gastrointestinal Tract
Humans
Liver*
Male
Melanoma*
Neoplasm Metastasis
Neuroendocrine Tumors*
Pancreas*
Pancreatic Neoplasms
Physical Examination
Skin
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