Soonchunhyang Med Sci.  2018 Jun;24(1):88-91. 10.0000/sms.2018.24.1.88.

Primary Extragastrointestinal Stromal Tumor of Retroperitoneum: Poor Response to Tyrosine Kinase Inhibitor

Affiliations
  • 1Division of Hematology and Oncology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. redmin07@gmail.com

Abstract

Gastrointestinal stromal tumors (GIST) are the most common sarcomas arising in the gastrointestinal tract. Stromal tumors arising outside the gastrointestinal tract are known as extragastrointestinal stromal tumors (EGIST). EGISTs may occur in omentum, mesentery, or retroperitoneum and are histologically and immunophenotypically similar to that in GISTs. EGISTs are very rare, so pathogenesis, incidence, and prognosis of EGISTs are not defined yet. In particular, there are a few reported literatures on the treatment of metastatic EGISTs. I report a case of a primary EGIST of the retroperitoneum with lung metastasis surgically removed and treated with tyrosine kinase inhibitor.

Keyword

Gastrointestinal stromal tumors; Retroperitoneum; Protein-tyrosine kinases

MeSH Terms

Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Incidence
Lung
Mesentery
Neoplasm Metastasis
Omentum
Prognosis
Protein-Tyrosine Kinases*
Sarcoma
Tyrosine*
Protein-Tyrosine Kinases
Tyrosine
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