Int J Oral Biol.
2018 Jun;43(2):53-59. 10.11620/IJOB.2018.43.2.053.
Single Molecule Method for Molecular Biology
- Affiliations
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- 1Department of Oral Biochemistry and Molecular Biology, Kyung Hee University, Seoul 02447, South Korea.
- 2KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, South Korea. che.jeong@kist.re.kr
- 3Center for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, South Korea.
- KMID: 2437355
- DOI: http://doi.org/10.11620/IJOB.2018.43.2.053
Abstract
- In order to understand biological phenomena accurately, single molecule techniques using a physical research approach to molecular interactions have been developed, and are now widely being used to study complex biological processes. In this review, we discuss some of the single molecule methods which are composed of two major parts: single molecule spectroscopy and manipulation. In particular, we explain how these techniques work and introduce the current research which uses them. Finally, we present the oral biology research using the single molecule methods.
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