Korean J Dermatol.
2018 Jan;56(1):49-52.
Crohn's Disease Initially Presenting as Vulvar Swelling
- Affiliations
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- 1Department of Dermatology, Konyang University College of Medicine, Daejeon, Korea. mabie@kyuh.ac.kr
Abstract
- Crohn's disease is a chronic granulomatous disease involving any part of gastrointestinal tract. The skin is a common site of extraintestinal involvement in Crohn's disease. The most common sites of cutaneous involvement in Crohn's disease are the perineal and perianal areas. Cutaneous Crohn's disease is relatively common among those previously diagnosed with gastrointestinal Crohn's disease. A 22-year-old woman presented with a history of a tender erythematous swelling on the vulva, predominantly on the right side, for several months. She had no previous medical history, including Crohn's disease. Histopathologic examination on the right side of labium majus showed upper dermal edema and granulomatous non-caseating necrosis composed of multinucleated giant cells, as well as perivascular and interstitial lymphoplasmocytic infiltration in the dermis. Under gastroenterology consultation, endoscopic examination was performed. Colon biopsy revealed chronic inflammation with lymphoplasmocytic infiltration, consistent with the active stage of Crohn's disease. Herein, we report a rare case of Crohn's disease initially presenting as vulvar swelling.
