Korean J Dermatol.  1992 Apr;30(2):267-271.

A case of Crohn's disease of the vulva

Abstract

Crohns disease is a granulomatous isease of the gastrointetin 1 tract, especially terminal ileum, but may involve the lip, mouth, anus, skin, liver and bone. The skin is a common site of extraintestinal involvement in Crohns disease, with the perianil, perineal, and peristomal areas most frequently affected. Vulvar involvement, however, is an uncommon extraintestinal manifestantion of Crohns disease. We report a case of a 16-year-old girl with Crohns disease of the vulva and perianal region. A histopathologic study of the descending colon and vulvar skin showed noncaseating granulomatous reactions composed of lymphocytes, epithelioidell and giant cells. We were able to make the diagnosis of Crohns disease of the vulvar and the patient was treated with prednisolone and metronidazole.

Keyword

Crohns disease; Vulvar involvement

MeSH Terms

Adolescent
Anal Canal
Colon, Descending
Crohn Disease*
Diagnosis
Female
Giant Cells
Humans
Ileum
Lip
Liver
Lymphocytes
Metronidazole
Mouth
Prednisolone
Skin
Vulva*
Metronidazole
Prednisolone
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