Korean J Blood Transfus.  2018 Dec;29(3):240-252. 10.17945/kjbt.2018.29.3.240.

Viscoelastic Coagulation Test Guided Therapy for a Strategy to Reduce Transfusions

• Park SY

• KMID: 2435618
• DOI: http://doi.org/10.17945/kjbt.2018.29.3.240

Abstract

Viscoelastic coagulation tests provide simultaneous measurements of multiple aspects of whole-blood coagulation, including interactions between the plasma components and cellular components of the coagulation cascade. This can be carried out immediately using a point of care technique. Viscoelastic tests could predict the patient's outcome, including mortality, and detect coagulopathy more sensitively, resulted in reduced blood loss. The transfusion strategy based on the viscoelastic parameters rather than a conventional coagulation test has been shown to reduce the transfusion requirements. Although there are concerns about the reliability and accuracy of this method, viscoelastic tests, including ROTEM, would be a useful method to guide patient blood management strategies.

Keyword

Blood coagulation disorders; Blood coagulation tests; Blood transfusion; Thromboelastography

MeSH Terms

Blood Coagulation Disorders
Blood Coagulation Tests
Blood Transfusion
Humans
Methods
Mortality
Plasma
Point-of-Care Systems
Thrombelastography