J Korean Soc Neonatol.  2011 May;18(1):34-41. 10.5385/jksn.2011.18.1.34.

Anticoagulation Therapy, Thrombolytic Therapy, and Use of Blood Products in Neonates

• Choi CW

• KMID: 2188455
• DOI: http://doi.org/10.5385/jksn.2011.18.1.34

Abstract

Neonatal coagulation disorders and thromboembolism require timely management. Failure to treat these conditions at the appropriate time may lead to death or the development of significant long-term sequelae. However, most current guidelines for managing neonatal coagulation disorders and thromboembolism are empiric and not based on randomized clinical trials. Thus, it is not easy to choose an appropriate management strategy for these conditions in clinical settings. In this review, therapeutic guidelines currently utilized in clinics and novel therapeutic options still under investigation are presented and reviewed.

Keyword

Neonate; Coagulation disorder; Thromboembolism; Anti-coagulation therapy

MeSH Terms

Humans
Infant, Newborn
Thromboembolism
Thrombolytic Therapy