J Korean Burn Soc.  2018 Dec;21(2):59-62. 10.0000/jkbs.2018.21.2.59.

Topical Administration of the Recombinant Human Epidermal Growth Factor (EGF) Containing Ointment on the Tendon Exposed Skin Defect in Foot Digit: A Case Report

• Jeon M
• Kim SY

• KMID: 2435192
• DOI: http://doi.org/10.0000/jkbs.2018.21.2.59

Abstract

Contact burn is usually caused by prolonged contact to hot material and results in deep dermal injury. As a result, skin and soft tissue defects occur, and coverage of defect is required. When defect is located in the foot phalanxes, reconstruction becomes more challenging owing to anatomical features. If the patient has medical histories such as diabetes mellitus, peripheral arterial obstructive disease, or chronic kidney disease, peripheral circulation may be worsened, and reconstruction becomes more difficult. We present the case of a patient with contact burn wound on his foot phalanxes and dorsum, where extensor digitorum tendons were exposed. Initial trial of skin graft was failed and they were completely epithelialized through secondary-intention healing with the administration of ointment containing recombinant human epidermal growth factor.

Keyword

Burns; Wound healing; Re-epithelialization; Epidermal growth factor

MeSH Terms

Administration, Topical*
Arterial Occlusive Diseases
Burns
Diabetes Mellitus
Epidermal Growth Factor*
Foot*
Humans*
Re-Epithelialization
Renal Insufficiency, Chronic
Skin*
Tendons*
Transplants
Wound Healing
Wounds and Injuries
Epidermal Growth Factor