J Neurocrit Care.  2018 Dec;11(2):134-136. 10.18700/jnc.180073.

A Variant Guillain-Barré Syndrome with Anti-Ganglioside Complex Antibody

• Huh SY
• Lee SY
• Lee JH
• Lee WG
• Kim JK
• Yoon BA
• Kim NJ

• KMID: 2434841
• DOI: http://doi.org/10.18700/jnc.180073

Abstract

BACKGROUND
Recently, anti-ganglioside complex (GSC) antibodies were discovered among the various subtypes of Guillain-Barré syndrome. GSC is the novel glycoepitopes formed by two individual ganglioside molecules.
CASE REPORT
We present a 36-year-old man with overlap Miller Fisher syndrome and acute bulbar palsy who had anti-GSC antibody that provided diagnostic robustness.
CONCLUSION
Anti-GSC testing could be considered important in patients who show atypical manifestation with negative antibody reaction against each constituent ganglioside.

Keyword

Guillain-Barre syndrome; Miller Fisher syndrome; Antibodies; Gangliosides

MeSH Terms

Adult
Antibodies
Bulbar Palsy, Progressive
Gangliosides
Guillain-Barre Syndrome*
Humans
Miller Fisher Syndrome
Antibodies
Gangliosides

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