J Korean Neurosurg Soc.  2019 Jan;62(1):71-82. 10.3340/jkns.2018.0012.

Parkinson's Disease as Risk Factor in Osteoporosis and Osteoporotic Vertebral Fracture : Prevalence Study Using National Inpatient Sample Database in Korea

• Lee JY
• Lim NG
• Chung CK
• Lee JY
• Kim HJ
• Park SB

• KMID: 2434348
• DOI: http://doi.org/10.3340/jkns.2018.0012

Abstract

OBJECTIVE
To determine the prevalence of osteoporosis (OP) and osteoporotic vertebral fracture (OVF) in people with Parkinson's disease (PD) in Korea and its association with socioeconomic status.
METHODS
Using Health Insurance Review and Assessment Service-National Inpatient Sample (HIRA-NIS) data from 2009 to 2013, we estimated the annual prevalence of PD, OP, and OVF and investigated its association with socioeconomic status using data from National Health Insurance (NHI) beneficiaries and Medical Aid (MA) recipients. This study was supported by research funding from Korean Society for Bone and Mineral Research 2015. There were no study-specific biases related to conflicts of interest.
RESULTS
The number of PD patients in the HIRA-NIS increased each year from 2009 to 2013. Among patients with PD, the standardized prevalence rates of OP and OVF increased from 2009 to 2013; from 23.2 to 27.8 and from 2.8 to 4.2, respectively. Among patients with PD with OP, the prevalence of OVF were 12.2% and 15.1% in 2009 and 2013, respectively. The standardized prevalence rates of PD with OP and PD with OVF were significantly higher in MA recipients than in NHI beneficiaries.
CONCLUSION
The prevalence of PD both with OP and with OVF increased and the prevalence was higher in MA recipients than in NHI beneficiaries. These findings may suggest that age over 65 years, female and low income may be a significant factor related to PD occurring with OP and OVF.

Keyword

Parkinson disease; Osteoporosis; Fractures, Bone

MeSH Terms

Bias (Epidemiology)
Cross-Sectional Studies*
Female
Financial Management
Fractures, Bone
Humans
Inpatients*
Insurance, Health
Korea*
Miners
National Health Programs
Osteoporosis*
Parkinson Disease*
Prevalence*
Risk Factors*
Social Class

Figure

• 

  Fig. 1. Framework of this study. *The number of parentheses mean the setimate numbers to the Korean populations. † Per 100000 Korean people. HIRANIS : Health Insurance Review and Assessment Service-National Inpatient Sample, PD : Parkinson's disease, OP : osteoporosis, SPR : standardized prevalence rate, OVF : osteoporotic vertebral fracture.

Reference

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