Korean J Pediatr.  2018 Nov;61(11):339-347. 10.3345/kjp.2018.06996.

Acute kidney injury and continuous renal replacement therapy in children; what pediatricians need to know

• Cho MH
• Kang HG

• KMID: 2433701
• DOI: http://doi.org/10.3345/kjp.2018.06996

Abstract

Acute kidney injury (AKI) is characterized by abrupt deterioration of renal function, and its diagnosis relies on creatinine measurements and urine output. AKI is associated with higher morbidity and mortality, and is a risk factor for development of chronic kidney disease. There is no proven medication for AKI. Therefore, prevention and early detection are important. Physicians should be aware of the risk factors for AKI and should monitor renal function in high-risk patients. Management of AKI includes optimization of volume status and renal perfusion, avoidance of nephrotoxic agents, and sufficient nutritional support. Continuous renal replacement therapy is widely available for critically ill children, and this review provides basic information regarding this therapy. Long-term follow-up of patients with AKI for renal function, blood pressure, and proteinuria is recommended.

Keyword

Acute kidney injury; Child; Renal replacement therapy

MeSH Terms

Acute Kidney Injury*
Blood Pressure
Child*
Creatinine
Critical Illness
Diagnosis
Follow-Up Studies
Humans
Mortality
Nutritional Support
Perfusion
Proteinuria
Renal Insufficiency, Chronic
Renal Replacement Therapy*
Risk Factors
Creatinine