Korean J Dermatol.  2019 Jan;57(1):28-31.

Proliferative Myositis on the Tongue

Affiliations
  • 1Department of Dermatology, College of Medicine, Dankook University, Cheonan, Korea. ivymyung@hanmail.net

Abstract

Proliferative myositis is a rare, benign, probably pseudosarcomatous fibroblastic proliferation that typically presents as a rapidly growing soft tissue mass. Its relative rarity, fast growth rate, and unique histopathologic findings may lead to misdiagnosis as a malignant lesion and unnecessary radical surgical excision. A 57-year-old female presented with a non-tender, well-defined, indurated, solitary, hard papule on the median sulcus of the tongue for 2 weeks. Histologic examination revealed numerous fibroblastic or myofibroblastic spindle cells and large ganglion-like cells infiltrating between and around the muscle fascicles. Immunohistochemical staining showed positivity for vimentin, smooth muscle actin, and CD68 and negativity for S-100. Based on these characteristic clinical findings and histopathologic features, the patient was diagnosed with proliferative myositis. Here, we report a rare case of proliferative myositis on the tongue and recommend considering proliferative myositis in the differential diagnosis when a physician encounters a rapidly grown soft tissue mass.

Keyword

Proliferative myositis; Pseudosarcoma; Tongue

MeSH Terms

Actins
Diagnosis, Differential
Diagnostic Errors
Female
Fibroblasts
Humans
Middle Aged
Muscle, Smooth
Myofibroblasts
Myositis*
Tongue*
Vimentin
Actins
Vimentin
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