Chonnam Med J.  2019 Jan;55(1):70-72. 10.4068/cmj.2019.55.1.70.

Paired Box Gene 8 (Pax8) Is also an Immunomarker of B-Cell Lineage Which Can Be Source of Diagnostic Pitfalls

• Gasparri P
• Roncati L

• KMID: 2432262
• DOI: http://doi.org/10.4068/cmj.2019.55.1.70

Abstract

No abstract available.

MeSH Terms

B-Lymphocytes*

Figure

• 

  FIG. 1 Reactive lymphadenitis (A, hematoxylin & eosin; 4×): the germinal centers, the mantles and the marginal zone are brown-stained by immunohistochemistry for PAX8 (B, clone MRQ-50, Ventana; 5×) and PAX5 (C, clone SP34, Ventana; 5×) in an overlapping manner involving the B-cell nuclei. Germinal center-derived lymphoma (D, 4×), mantle cell lymphoma (E, 4×) and marginal zone lymphoma (F, 4×) are strongly labeled by PAX8 immunohistochemistry [chromogen: 3,3′ diaminobenzidine tetrahydrochloride hydrate].

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