J Audiol Otol.  2018 Oct;22(4):248-252. 10.7874/jao.2018.00171.

Pyoderma Gangrenosum of the Preauricular Area with Ulcerative Colitis: A Case Report and Review

• Chae HS
• Han SM
• Lee HN
• Jeon HJ
• Seo YJ

• KMID: 2428994
• DOI: http://doi.org/10.7874/jao.2018.00171

Abstract

Pyoderma gangrenosum (PG) is primarily, a sterile, inflammatory, neutrophilic dermatosis, characterized by recurrent cutaneous ulceration with mucopurulent or hemorrhagic exudate. The incidence of PG is uncertain, but it is estimated to be about 3-10 patients per million per year. It occurs most commonly on the lower legs, but has been reported at other sites of the body as well. The causes of PG are unknown, but about 50-70% of cases are associated with other diseases, mainly inflammatory bowel disease. We hereby report a case of PG in a 21-year-old male, with a history of ulcerative colitis (UC). After appropriate diagnostic methods including biopsy for pathologic confirmation, sigmoidoscopy and computed tomography, we excluded other diseases and the lesion was diagnosed as PG. We then carried out regular dressing of the wound, while UC was treated with steroid and immunosuppressant medication, with inputs from the department of gastroenterology during the hospital stay. There occurred recurrence of the skin lesion, 7 months after discharge, after which they improved. UC has been in the remission state as per the follow-up, since 2 years.

Keyword

Pyoderma gangrenosum; Preauricular area; Inflammatory bowel disease; Preauricular sinus

MeSH Terms

Bandages
Biopsy
Colitis, Ulcerative*
Exudates and Transudates
Follow-Up Studies
Gastroenterology
Humans
Incidence
Inflammatory Bowel Diseases
Leg
Length of Stay
Male
Neutrophils
Pyoderma Gangrenosum*
Pyoderma*
Recurrence
Sigmoidoscopy
Skin
Skin Diseases
Ulcer*
Wounds and Injuries
Young Adult