J Korean Med Sci.  2018 Dec;33(50):e319. 10.3346/jkms.2018.33.e319.

Severe Fever with Thrombocytopenia Syndrome Patients with Hemophagocytic Lymphohistiocytosis Retrospectively Identified in Korea, 2008–2013

Affiliations
  • 1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
  • 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea. socioliberal@yahoo.co.kr
  • 3Department of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.
  • 4Department of Laboratory Medicine, Pusan National University School of Medicine, Busan, Korea.

Abstract

The incidence of severe fever with thrombocytopenia syndrome (SFTS) has increased in Korea since a first report in 2013. We investigated whether SFTS existed before 2013 using real-time reverse transcription polymerase chain reaction and stored blood samples from febrile patients with thrombocytopenia. Four cases of SFTS were identified, with the earliest occurring in 2008.

Keyword

SFTS; Phlebovirus; Hemophagocytic Lymphohistiocytosis; Fever; Thrombocytopenia

MeSH Terms

Fever*
Humans
Incidence
Korea*
Lymphohistiocytosis, Hemophagocytic*
Phlebovirus
Polymerase Chain Reaction
Retrospective Studies*
Reverse Transcription
Thrombocytopenia*
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