J Nutr Health.  2018 Oct;51(5):414-422. 10.4163/jnh.2018.51.5.414.

Association between nutrient intakes and prevalence of depressive disorder in Korean adults: 2014 Korean National Health and Nutrition Examination Survey

• Park SJ
• Choi JH
• Lee JY
• Lee C
• Lee HJ

• KMID: 2427764
• DOI: http://doi.org/10.4163/jnh.2018.51.5.414

Abstract

OBJECTIVE
Dietary nutrients may play a significant role in depressive disorders. However, sufficient evidences in epidemiological studies are limited. We investigated the cross-sectional association between dietary nutrients and the prevalence of depressive disorder in Korean adults using representative Korean data.
METHODS
Participants were 2,938 adults aged 19 ~ 64 years from the Korea National Health and Nutrition Examination Survey (KNHANES) conducted in 2014. Dietary intakes were assessed using 24-h recall method. Depressive disorder was assessed using Patients Health Questionnaire-9 (PHQ-9, self-depression test) as applied in 2014 KNHANES only. We defined depressive disorder as having a PHQ-9 score of ≥10, which was characterized as moderate depression and more. A multivariate logistic regression analysis was performed to estimate the adjusted odd ratios (ORs) and 95% confidence interval (CIs) of depressive disorder.
RESULTS
Among the 2,938 subjects, 170 were identified as having depressive disorder. The multivariate-adjusted regression analysis demonstrated that the risk of depression was significantly associated with riboflavin (OR = 0.44, 95% CI: 0.24-0.85, p for trend = 0.018), thiamin (OR = 0.48, 95% CI: 0.23-0.99, p for trend = 0.045), and vitamin C (OR = 0.57, 95% CI: 0.34-0.95, p for trend = 0.025) in the highest versus lowest tertiles of intake.
CONCLUSION
The high consumption of riboflavin, thiamin, and vitamin C was associated with the low prevalence of depressive disorder in Korean adults.

Keyword

depressive disorder; riboflavin; thiamin; vitamin C; KNHANES

MeSH Terms

Adult*
Ascorbic Acid
Depression
Depressive Disorder*
Epidemiologic Studies
Humans
Korea
Logistic Models
Methods
Nutrition Surveys*
Prevalence*
Riboflavin
Ascorbic Acid
Riboflavin

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