Allergy Asthma Respir Dis.  2018 Nov;6(6):290-294. 10.4168/aard.2018.6.6.290.

Clinical presentation of croup in children according to causative viruses

• Kim GE
• Shin SW
• Choi HJ
• Choi BG

• KMID: 2427487
• DOI: http://doi.org/10.4168/aard.2018.6.6.290

Abstract

PURPOSE
We evaluated the clinical features of croup in children according to viral etiology.
METHODS
This study enrolled pediatric patients with croup, who showed positive results on respiratory virus reverse transcriptase polymerase chain reaction performed between January 2012 and December 2017. We retrospectively reviewed the medical records.
RESULTS
A total of 179 patients (119 boys and 60 girls) were enrolled with the mean age of 18.9±14.7 months. The viruses commonly identified were parainfluenza, respiratory syncytial virus, rhinovirus, and influenza. Among these 4 viruses, patients with rhinovirus infection showed significantly shorter fever and admission durations. Patients with parainfluenza infection showed significantly lower incidences of epinephrine nebulization and patients with influenza infections showed significantly higher incidences of steroid treatment.
CONCLUSION
Clinical manifestations of croup differ according to causative viruses. Further studies should be conducted to evaluate the severity and prognosis of croup according to viral etiology.

Keyword

Croup; Respiratory virus; Child

MeSH Terms

Child*
Croup*
Epinephrine
Fever
Humans
Incidence
Influenza, Human
Medical Records
Paramyxoviridae Infections
Prognosis
Respiratory Syncytial Viruses
Retrospective Studies
Reverse Transcriptase Polymerase Chain Reaction
Rhinovirus
Epinephrine

Figure

• 

  Fig. 1 Distribution of detected virus of patients with croup. PIV, parainfluenza virus; RSV, respiratory syncytial virus; hRV, human rhinovirus; IFV, influenzavirus; hBoV, human bocavirus; hMPV, human metapneumonvirus; hCoV, human coronavirus; ADV, Adenovirus.

• 

  Fig. 2 Distribution of patients with croup by month. PIV, parainfluenza virus; RSV, respiratory syncytial virus; hRV, human rhinovirus; IFV, influenzavirus.

• 

  Fig. 3 The Westley score of patients with croup. PIV, parainfluenza virus; RSV, respiratory syncytial virus; hRV, human rhinovirus; IFV, influenzavirus.

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