J Korean Neurosurg Soc.  1976 Jun;5(1):179-184.

Malignant Schwannoma Associated with Von Recklinghausen' Disease

Affiliations
  • 1Department of Neurosurgery, National Medical Center, Seoul, Korea.

Abstract

Malignant peripheral nerve tumors are very rare and derived from the neurofibromatosis in about 13%. There are two classes of malignant tumors in the peripheral nerve, one those of mesoblastic origin, is far most common and made up of malignant neurofibroma and much common fibrosarcoma, and metastasis in 20% of fibrosarcoma, and the other is neuroepithelial origin. These are characterized by increased cellularity, atypical form of cells, mitoses and invasiveness. The choice treatment is radical removal of the tumor, and not affected the prognosis by radiation or chemotherapy. We have been recently experienced of one case of malignant schwannoma on the cervical roots in a case of von Recklinhausen's disease.


MeSH Terms

Drug Therapy
Fibrosarcoma
Mitosis
Neoplasm Metastasis
Neurilemmoma*
Neurofibroma
Neurofibromatoses
Peripheral Nerves
Peripheral Nervous System Neoplasms
Prognosis
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