J Korean Orthop Assoc.  2018 Oct;53(5):381-392. 10.4055/jkoa.2018.53.5.381.

Platelet-Rich Plasma Injection

• Yoon JY
• Jo CH

• KMID: 2424096
• DOI: http://doi.org/10.4055/jkoa.2018.53.5.381

Abstract

Platelet-rich plasma (PRP) supplies numerous growth factors from concentrated platelets required to promote the healing process of injured or degenerated tissue. PRP is already a popular option to treat a variety of musculoskeletal injuries and diseases, even though the precise mechanism of action is not completely understood. Varying outcomes, from favorable to poor, after PRP injection may arise from interstudy differences with respect to 4Ds (Drug [PRP], Delivery [application method], Donor [patients], and Disease [stage of rotator cuff disease]). In addition, there is no standard treatment regimen (injection location, number, interval, volume). Therefore, precise outcome measures as well as long-term follow-up are required to accurately evaluate the efficacy.

Keyword

platelet-rich plasma; injection; osteoarthritis; tendinopathy; rotator cuff tear

MeSH Terms

Equipment and Supplies
Follow-Up Studies
Humans
Intercellular Signaling Peptides and Proteins
Osteoarthritis
Outcome Assessment (Health Care)
Platelet-Rich Plasma*
Rotator Cuff
Tendinopathy
Tissue Donors
Intercellular Signaling Peptides and Proteins

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