Korean J Health Promot.  2018 Sep;18(3):127-137. 10.15384/kjhp.2018.18.3.127.

Gender Perspectives on the Relationship between Red and Processed Meat Intake and Colorectal Cancer: A Systematic Review and Meta-Analysis

• Lee HN
• Lee JE
• Kang M
• Shim JE
• Paik HY

• KMID: 2421871
• DOI: http://doi.org/10.15384/kjhp.2018.18.3.127

Abstract

BACKGROUND
Men and women choose different food items, and consume different amounts of food, due to biological, cultural, and social differences. However, when dietary assessment instruments are developed, gender differences in food selection and/or the portion sizes are often not considered.
METHODS
Prospective cohort studies with men and women that examined the association between red or processed meat intake and colorectal cancer and published up to July 2017, were identified using PubMed. Studies were categorized as gender-specific (GS) group if the Food Frequency Questionnaire was developed using gender-specific data, and as not gender-specific (NGS) group if not gender-specific data were used.
RESULTS
For cohort studies that reported combined intake estimates of men and women, a 100 g/day increment in red and processed meat intake was positively associated with a risk of colorectal or colon cancer in GS group (relative risk [RR], 1.23; 95% confidence interval [CI], 1.14-1.32) but not in NGS group (RR, 1.13; 95% CI, 0.90-1.35). For processed meat, the RR for 50 g/day increase was 1.28 (95% CI, 1.15-1.40) in GS group and 1.15 (95% CI, 1.03-1.27) in NGS group.
CONCLUSIONS
Gender differences need to be considered during development of dietary assessment tools because this may improve the quality of the findings of nutritional epidemiological studies.

Keyword

Gender; Red meat; Processed meat; Colorectal neoplasms; Surveys and questionnaires

MeSH Terms

Cohort Studies
Colonic Neoplasms
Colorectal Neoplasms*
Epidemiologic Studies
Female
Food Preferences
Humans
Male
Meat*
Portion Size
Prospective Studies
Red Meat
Surveys and Questionnaires

Figure

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  Figure 1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart. Screening and selection of studies analysing the association between meat (red and processed/red/processed) intake and Colorectal cancer risk.

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  Figure 2. Dose-response meta-analysis between red and processed meat and colorectal or colon cancer in male and female combined cohort studies (P for difference=0.340).

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  Figure 3. Highest vs. lowest meta-analysis between red and processed meat and colorectal or colon cancer in male and female combined cohort studies (P for difference=0.022).

Reference

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