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Management of isolated para-aortic lymph node recurrence after surgery for colorectal cancer

Kim YI, Park IJ, Park JH, Kim TW, Ro JS, Lim SB, Yu CS, Kim JC

PURPOSE: The rare incidence of isolated para-aortic lymph node (PALN) recurrence of colorectal cancer has precluded the formulation of treatment guidelines. This study evaluated and compared the effects of different...
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Upregulated Long Noncoding RNA LINC01234 Predicts Unfavorable Prognosis for Colorectal Cancer and Negatively Correlates With KLF6 Expression

Jiang X, Zhu Q, Wu P, Zhou F, Chen J

BACKGROUND: LINC01234, a long noncoding RNA (lncRNA), is overexpressed in several cancers, including colorectal cancer (CRC). We investigated the role of LINC01234 in CRC development and confirmed its correlation with...
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Clinical Impact of Myeloid-Derived Suppressor Cells, Lymphocyte Subsets, and Neutrophil-to-Lymphocyte Ratio in Patients with Colorectal Cancer

Kang MG, Kim CH, Kim SH, Shin JH, Kim HR, Shin MG

BACKGROUND: Preoperative myeloid-derived suppressor cells (MDSCs), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte subsets have been reported to be associated with the clinical outcomes in colorectal cancer (CRC). However, studies on the...
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Patterns of antibiotics and pathogens for anastomotic leakage after colorectal cancer surgery

Yang G, Kim CW, Lee SH

PURPOSE: Anastomotic leakage (AL) is a type of intra-abdominal infection (IAI) which requires appropriate antibiotics with proper intervention. This study aimed to improve the appropriateness of antibiotic treatment by assessing...
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Mucinous carcinoma is a predictive factor for the risk of open conversion from laparoscopic colectomy in colorectal cancer

Seo AJ, Shin JK, Park YA, Huh JW, Cho YB, Kim HC, Yun SH, Lee WY

PURPOSE: Although laparoscopic surgery is widely accepted in the treatment of colorectal cancer, conversion to open surgery is associated with the rate of unfavorable outcomes. The aim of this study...
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Detection of KRAS mutations in plasma cell-free DNA of colorectal cancer patients and comparison with cancer panel data for tissue samples of the same cancers

Min S, Shin S, Chung YJ

Robust identification of genetic alterations is important for the diagnosis and subsequent treatment of tumors. Screening for genetic alterations using tumor tissue samples may lead to biased interpretations because of...
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Risk Factors for Colorectal Cancer in Korea: A Population-Based Retrospective Cohort Study

Nam S, Choi YJ, Kim DW, Park EC, Kang JG

PURPOSE: The incidence of colorectal cancer in Korea has recently increased, making it the second most common cancer in men and the third most common cancer in women. Risk factors...
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Immunological Differences Between Right-Sided and Left-Sided Colorectal Cancers: A Comparison of Embryologic Midgut and Hindgut

Kwak HD, Ju JK

PURPOSE: There are known differences in embryology, clinical symptoms, incidences, molecular pathways involved, and oncologic outcomes of right-sided and left-sided colorectal cancers. However, immunologic study has only been characterized for...
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Development and Evaluation of Enhanced Recovery After Surgery Program for Patients with Colorectal Cancer Surgery

Kim EJ, Park JS

PURPOSE: This study aimed to develop and evaluate the effectiveness of the Enhanced Recovery After Surgery (ERAS) program for colorectal cancer surgery patients. METHODS: This program was developed using ADDIE model....
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Evaluating the recent developments in palliative chemotherapy for metastatic colorectal cancer

Baek SK, Lee KT, Bae SB, Lee SC

The incidence of colorectal cancer (CRC) has increased. CRC is the third most common cancer and the fourth most common cause of cancer-related deaths in Korea. Palliative chemotherapy can be...
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Hepatic resection after neoadjuvant chemotherapy for patients with liver metastases from colorectal cancer: need for cautious planning

Kim YI, Park IJ, Kim JE, Kim SY, Park JH, Lee JH, Ha TY, Hong YS, Kim SY, Kim TW, Lim SB, Yu CS, Kim JC

PURPOSE: Current neoadjuvant chemotherapy (NAC) may enable therapies such as surgical resection and local ablation of metastases in patients with colorectal liver metastasis (CLM). We evaluated outcomes in CLM patients...
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Parthenolide inhibits transforming growth factor β1-induced epithelial-mesenchymal transition in colorectal cancer cells

Zhu SM, Park YR, Seo SY, Kim IH, Lee ST, Kim SW

BACKGROUND/AIMS: Transforming growth factor-β1 (TGF-β1) induction of epithelial-mesenchymal transition (EMT) is one of the mechanisms by which colorectal cancer (CRC) cells acquire migratory and invasive capacities, and subsequently metastasize. Parthenolide...
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Influence of Hospital Nurse Staffing Levels on the Colorectal Cancer Evaluation Grades, Mortality, and Length of Stay

Kim Y, Kim SY

PURPOSE: In Korea, cancer is the leading cause of death, and colorectal cancer accounts for a third of deaths caused by cancer. This study aimed to analyze the influence of...
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Nomogram Development and External Validation for Predicting the Risk of Lymph Node Metastasis in T1 Colorectal Cancer

Oh JR, Park B, Lee S, Han KS, Youk EG, Lee DH, Kim DS, Lee DS, Hong CW, Kim BC, Kim B, Kim MJ, Park SC, Sohn DK, Chang HJ, Oh JH

PURPOSE: Predicting lymph node metastasis (LNM) risk is crucial in determining further treatment strategies following endoscopic resection of T1 colorectal cancer (CRC). This study aimed to establish a new prediction...
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Which strategy is better for resectable synchronous liver metastasis from colorectal cancer, simultaneous surgery, or staged surgery? Multicenter retrospective analysis

Kye BH, Lee SH, Jeong WK, Yu CS, Park IJ, Kim HR, Kim J, Lee IK, Park KJ, Choi HJ, Kim HY, Baek JH, Lee YS

PURPOSE: The optimal treatment for synchronous liver metastasis (LM) from colorectal cancer (CRC) depends on various factors. The present study was intended to investigate the oncologic outcome according to the...
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Clinicopathological Characterization and Prognostic Implication of SMAD4 Expression in Colorectal Carcinoma

Yoo SY, Lee JA, Shin Y, Cho NY, Bae JM, Kang GH

BACKGROUND: SMAD family member 4 (SMAD4) has gained attention as a promising prognostic factor of colorectal cancer (CRC) as well as a key molecule to understand the tumorigenesis and progression...
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Comparison of the Response Evaluation Criteria in Solid Tumors with Volumetric Measurement for Evaluation of Response and Overall Survival with Liver Metastases from Colorectal Cancer

Lee IS, Choi SJ, Seo CR, Kim JS

PURPOSE: The aim of this study was to compare the measurements of diameter and volume of hepatic metastases from CT images with the overall survival and tumor response, in patients...
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Female hormones and the risk of colorectal neoplasm

Jung Y

No abstract available.
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Impact of Patient’s Pain and Fatigue on Decision of Discharge After Laparoscopic Surgery for Colorectal Cancer

Lee G, Lee JS, Kim JH, Hwang DY, Lee YS

PURPOSE: Hospital stays after laparoscopic surgery for colorectal cancer tend to be much shorter than those after conventional open surgery. Many factors, including surgical outcomes and complications, are associated with...
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Sentinel Lymph Node Analysis in Colorectal Cancer Patients Using One-Step Nucleic Acid Amplification in Combination With Fluorescence and Indocyanine Green

Esposito F, Noviello A, Moles N, Coppola Bottazzi E, Baiamonte , Macaione I, Ferbo U, Lepore M, Miro A, Crafa F

PURPOSE: Analysis of the sentinel lymph node (SLN) in colorectal cancer (CRC) patients was proposed for more accurate staging and tailored lymphadenectomy. The aim of this study was to assess...
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