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Management of isolated para-aortic lymph node recurrence after surgery for colorectal cancer

Kim YI, Park IJ, Park JH, Kim TW, Ro JS, Lim SB, Yu CS, Kim JC

PURPOSE: The rare incidence of isolated para-aortic lymph node (PALN) recurrence of colorectal cancer has precluded the formulation of treatment guidelines. This study evaluated and compared the effects of different...
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Upregulated Long Noncoding RNA LINC01234 Predicts Unfavorable Prognosis for Colorectal Cancer and Negatively Correlates With KLF6 Expression

Jiang X, Zhu Q, Wu P, Zhou F, Chen J

BACKGROUND: LINC01234, a long noncoding RNA (lncRNA), is overexpressed in several cancers, including colorectal cancer (CRC). We investigated the role of LINC01234 in CRC development and confirmed its correlation with...
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Clinical Impact of Myeloid-Derived Suppressor Cells, Lymphocyte Subsets, and Neutrophil-to-Lymphocyte Ratio in Patients with Colorectal Cancer

Kang MG, Kim CH, Kim SH, Shin JH, Kim HR, Shin MG

BACKGROUND: Preoperative myeloid-derived suppressor cells (MDSCs), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte subsets have been reported to be associated with the clinical outcomes in colorectal cancer (CRC). However, studies on the...
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Clinicopathological Characterization and Prognostic Implication of SMAD4 Expression in Colorectal Carcinoma

Yoo SY, Lee JA, Shin Y, Cho NY, Bae JM, Kang GH

BACKGROUND: SMAD family member 4 (SMAD4) has gained attention as a promising prognostic factor of colorectal cancer (CRC) as well as a key molecule to understand the tumorigenesis and progression...
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Comparison of the Response Evaluation Criteria in Solid Tumors with Volumetric Measurement for Evaluation of Response and Overall Survival with Liver Metastases from Colorectal Cancer

Lee IS, Choi SJ, Seo CR, Kim JS

PURPOSE: The aim of this study was to compare the measurements of diameter and volume of hepatic metastases from CT images with the overall survival and tumor response, in patients...
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Female hormones and the risk of colorectal neoplasm

Jung Y

No abstract available.
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Impact of Patient’s Pain and Fatigue on Decision of Discharge After Laparoscopic Surgery for Colorectal Cancer

Lee G, Lee JS, Kim JH, Hwang DY, Lee YS

PURPOSE: Hospital stays after laparoscopic surgery for colorectal cancer tend to be much shorter than those after conventional open surgery. Many factors, including surgical outcomes and complications, are associated with...
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Sentinel Lymph Node Analysis in Colorectal Cancer Patients Using One-Step Nucleic Acid Amplification in Combination With Fluorescence and Indocyanine Green

Esposito F, Noviello A, Moles N, Coppola Bottazzi E, Baiamonte , Macaione I, Ferbo U, Lepore M, Miro A, Crafa F

PURPOSE: Analysis of the sentinel lymph node (SLN) in colorectal cancer (CRC) patients was proposed for more accurate staging and tailored lymphadenectomy. The aim of this study was to assess...
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The Impact of Patient’s Pain and Fatigue on the Discharge Decision After Laparoscopic Surgery for Colorectal Cancer

Jung WB

No abstract available.
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Clinical value of an adenosine triphosphate-based chemotherapy response assay in resectable stage III colorectal cancer

Kim CD, Kim SH, Jung SH, Kim JH

PURPOSE: ATP-based chemotherapy response assay (ATP-CRA) is a well-documented and validated technology that can individualize chemotherapy. This study was undertaken to assess the usefulness of ATP-CRA in advanced colorectal cancer...
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Colorectal cancer epidemiology in Korea

Shin A, Jang D, Choe S, Won YJ, Jung KW, Park JW, Jeong SY

Although colorectal cancer emerged as a major public health concern, its incidence as well as mortality are decreasing during recent years in Korea. Most important contributor for these reduction in...
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Long Non-Coding RNA LINC00525 Promotes the Stemness and Chemoresistance of Colorectal Cancer by Targeting miR-507/ELK3 Axis

Wang S, Li J, Yang X

BACKGROUND AND OBJECTIVES: This study aims to explore the effects of a long non-coding RNA, LINC00525, on colorectal cancer (CRC) and its underlying molecular mechanisms. METHODS: The qPCR, MTT, colony formation,...
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Association of visceral adiposity and insulin resistance with colorectal adenoma and colorectal cancer

Jung IS, Shin CM, Park SJ, Park YS, Yoon H, Jo HJ, Kim N, Lee DH

BACKGROUND/AIMS: To examine whether visceral adiposity serves as a risk factor for colorectal cancer (CRC) and colorectal adenomas. METHODS: Two hundred healthy subjects, 200 patients with colorectal adenoma, and 151 patients...
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Prevalence and risk factors of colorectal cancer in Asia

Wong MC, Ding H, Wang J, Chan PS, Huang J

Globally, colorectal cancer (CRC) is a substantial public health burden, and it is increasingly affecting populations in Asian countries. The overall prevalence of CRC is reported to be low in...
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Prognostic Implications of Extranodal Extension in Relation to Colorectal Cancer Location

Kim CW, Kim J, Park Y, Cho DH, Lee JL, Yoon YS, Park IJ, Lim SB, Yu CS, Kim JC

PURPOSE: Extranodal extension (ENE) is closely associated with the aggressiveness of both colon and rectal cancer. This study evaluated the clinicopathologic significance and prognostic impact of ENE in separate populations...
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A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-Line Chemotherapy in Metastatic Colorectal Cancer Patients

Kim Y, Kim TW, Han SW, Ahn JB, Kim ST, Lee J, Park JO, Park YS, Lim HY, Kang WK

PURPOSE: Simvastatin has demonstrated anti-tumor activity in preclinical studies via tumor cell senescence, apoptosis, and anti-angiogenesis. This phase II trial evaluated the efficacy and toxicity profile of conventional XELOX and...
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Genetic Risk Score, Combined Lifestyle Factors and Risk of Colorectal Cancer

Cho YA, Lee J, Oh JH, Chang HJ, Sohn DK, Shin A, Kim J

PURPOSE: Both genetic and lifestyle factors contribute to the risk of colorectal cancer, but each individual factor has a limited effect. Therefore, we investigated the association between colorectal cancer and...
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The Effect of Arginine Intake on Colorectal Cancer: a Systematic Review of Literatures

Karimian J, Hadi A, Salehi-sahlabadi A, Kafeshani

Colorectal cancer (CRC) is one of the major reasons of mortality in the worldwide. There is clear evidence that some amino acids such as arginine can improve CRC and its...
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Early-onset Colorectal Cancer

Jeong MA, Kang HW

The incidence of colorectal cancer (CRC) is increasing among young adults in several countries including the United States. Early-onset colorectal cancer (EO-CRC) is heterogenous group and appears to have a...
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The correlation between serum vascular endothelial growth factor (VEGF) and tumor VEGF receptor 3 in colorectal cancer

Goulart A, Ferreira C, Rodrigues , Coimbra B, Sousa N, Leão P

PURPOSE: Despite plasma biomarkers offering a number of advantages over tissue-based markers, the relationship between serum vascular endothelial growth factor (VEGF) and VEGF receptor (VEGF-R) tumor expression in colorectal cancer...
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