Ann Hepatobiliary Pancreat Surg.  2018 Aug;22(3):248-252. 10.14701/ahbps.2018.22.3.248.

How to prevent the postoperative pancreatic fistula with an ethylene vinyl alcohol copolymer (Onyx®): A proposal of a new technique

Affiliations
  • 1Oncological and General Surgery Unit, “St. Giuseppe Moscati” Hospital of National Relevance and High Specialty, Avellino, Italy. crafa@tiscali.it
  • 2Department of Radiology, “St. Giuseppe Moscati” Hospital of National Relevance and High Specialty, Avellino, Italy.

Abstract

BACKGROUNDS/AIMS
Despite the advances in identifying risk factors, improving operative technique, and postoperative patient care, pancreatic leakage after pancreatic resection remains a highly debated topic. The aim of this study is to describe our technique and our initial experience with the intraoperative embolization of the main pancreatic duct with an Ethylene Vinyl Alcohol Copolymer (Onyx®).
METHODS
Two patients of 63 and 64 years underwent pancreaticoduodenectomy for a cholangiocarcinoma of the extrahepatic bile duct and a pancreatic adenocarcinoma, respectively. At the time of pancreatic parenchyma resection, a Wirsung duct was identified and catheterized. A wirsungography was done and then, embolization with Onyx® was carried out under fluoroscopic control.
RESULTS
Neither of the patients developed a postoperative pancreatic fistula. They were discharged to home on the 17th and 18th postoperative day, respectively. At the last follow-up, no recurrence was found. The two patients became diabetics; both needed the support of supplementary pancreatic enzymes.
CONCLUSIONS
To our knowledge, we are the first to describe this technique, which seems safe and reliable. Studies on this subject with more patients are needed to confirm the validity of this procedure.

Keyword

Postoperative pancreatic fistula; Pancreaticoduodenectomy; Onyx®

MeSH Terms

Adenocarcinoma
Bile Ducts, Extrahepatic
Catheters
Cholangiocarcinoma
Follow-Up Studies
Humans
Pancreatic Ducts
Pancreatic Fistula*
Pancreaticoduodenectomy
Patient Care
Recurrence
Risk Factors
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