Tuberc Respir Dis.  2018 Jan;81(1):42-48. 10.4046/trd.2017.0118.

Development of Prediction Equation of Diffusing Capacity of Lung for Koreans

• Hwang YI
• Park YB
• Yoon HK
• Lim SY
• Kim TH
• Park JH
• Lee WY
• Park SJ
• Lee SW
• Kim WJ
• Kim KU
• Shin KC
• Kim DJ
• Kim HJ
• Kim TE
• Yoo KH
• Shim JJ

• KMID: 2420590
• DOI: http://doi.org/10.4046/trd.2017.0118

Abstract

BACKGROUND
The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans.
METHODS
Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study.
RESULTS
Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=−10.4433−0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507−0.02374×age (year)−0.00233×heights (cm). For women the prediction equations were described as followed: DLco=−12.8895−0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516−0.02219×age (year)−0.01377×heights (cm). All equations were internally validated by k-fold cross validation method.
CONCLUSION
In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

Keyword

Korean; Pulmonary Diffusing Capacity; Diffusion; Carbon Monoxide

MeSH Terms

Carbon Monoxide
Diffusion
Female
Humans
Korea
Linear Models
Lung*
Male
Methods
Nutrition Surveys
Pulmonary Diffusing Capacity
Smoke
Smoking
Thorax
Carbon Monoxide
Smoke

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